2-Bromo-4-(1-piperidinylmethyl)pyridine(CAS: 88046-02-0)

2-Bromo-4-(1-piperidinylmethyl)pyridine is a solid with a crystalline form. Its molecular weight is approximately 261.14 g/mol. This compound has limited water solubility but is more soluble in organic solvents like dimethylformamide (DMF) and acetonitrile. It is moderately reactive with strong nucleophiles and acidic conditions. The compound is stable under normal laboratory conditions but should be stored in a dry, cool place to prevent degradation.

2-Bromo-4-(1-piperidinylmethyl)pyridine is typically synthesized through the reaction of 4-(1-piperidinylmethyl)pyridine with bromine in the presence of a catalyst like iron(III) bromide. The reaction is performed under anhydrous conditions to improve selectivity and yield. The product is usually purified by recrystallization from hot ethanol followed by vacuum drying.

2-Bromo-4-(1-piperidinylmethyl)pyridine is used in pharmaceutical research for its potential as a precursor in the synthesis of new drugs. It may also find applications in the development of certain sensors and semiconductors due to its unique chemical properties. However, its specific industrial uses are still being explored.

When handling 2-Bromo-4-(1-piperidinylmethyl)pyridine, users should wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a well-ventilated area and handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up immediately using appropriate absorbent materials. For detailed information, refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS).