Methyl 3-amino-6-chloro-2-pyridinecarboxylate

Basic Information

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CAS Number

866807-26-3

Molecular Formula

C7H7ClN2O2

Molecular Weight

186.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC(=O)c1nc(Cl)ccc1N

InChI

InChI=1S/C7H7ClN2O2/c1-12-7(11)6-4(9)2-3-5(8)10-6/h2-3H,9H2,1H3

InChIKey

LGDVQMFMAURKDX-UHFFFAOYSA-N

LogP

1.1038000000000001

Topological Polar Surface Area

65.21 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

177

Synonyms & References

English

Methyl 3-amino-6-chloropicolinate
3-Amino-6-chloro-pyridine-2-carboxylic acid methyl ester
Methyl 3-amino-6-chloropicolite
methyl 3-amino-6-chloropyridine-2-carboxylate
LGDVQMFMAURKDX-UHFFFAOYSA-N
3617AC
PB13808
3-Amino-6-chloro-pyridine-2-carboxylic acid methyl

MDL Number

MFCD18259037

Customs Code

2933399090

FAQ

What are the physical and chemical properties of Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3)?

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is a crystalline solid with a molecular weight of approximately 219.64 g/mol. It has a solubility of about 1.5 g/L in water and is slightly soluble in common organic solvents. The compound is mildly reactive, particularly towards nucleophiles and can undergo substitution reactions. It is stable under normal laboratory conditions but should be stored away from strong oxidizing agents.

How is Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) typically synthesized?

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is typically synthesized via the reaction of 2-chloro-6-nitropyridine with methylamine followed by reduction of the nitro group to an amino group. The synthesis is carried out using a suitable reducing agent such as sodium borohydride. The yield is around 75-85%, and the reaction is highly selective.

What industries use Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3)?

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for the modification of polymer properties and in the sensor industry for developing new sensing materials.

What precautions should be taken when handling Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3)?

When handling Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3), it is important to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be carefully managed and cleaned up using appropriate methods. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.