Compound Q&A

How is Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) typically synthesized?

Answer

Methyl 3-amino-6-chloro-2-pyridinecarboxylate
Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is typically synthesized via the reaction of 2-chloro-6-nitropyridine with methylamine followed by reduction of the nitro group to an amino group. The synthesis is carried out using a suitable reducing agent such as sodium borohydride. The yield is around 75-85%, and the reaction is highly selective.

About

English Name Methyl 3-amino-6-chloro-2-pyridinecarboxylate
Molecular Formula C7H7ClN2O2
Molecular Weight 186.6 g/mol
SMILES COC(=O)c1nc(Cl)ccc1N
InChIKey LGDVQMFMAURKDX-UHFFFAOYSA-N
Last Updated: 2025-10-17 07:35

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