Methyl 3-amino-6-chloro-2-pyridinecarboxylate(CAS: 866807-26-3)

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is a crystalline solid with a molecular weight of approximately 219.64 g/mol. It has a solubility of about 1.5 g/L in water and is slightly soluble in common organic solvents. The compound is mildly reactive, particularly towards nucleophiles and can undergo substitution reactions. It is stable under normal laboratory conditions but should be stored away from strong oxidizing agents.

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is typically synthesized via the reaction of 2-chloro-6-nitropyridine with methylamine followed by reduction of the nitro group to an amino group. The synthesis is carried out using a suitable reducing agent such as sodium borohydride. The yield is around 75-85%, and the reaction is highly selective.

Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3) is used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry for the modification of polymer properties and in the sensor industry for developing new sensing materials.

When handling Methyl 3-amino-6-chloro-2-pyridinecarboxylate (CAS: 866807-26-3), it is important to wear personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. Spills should be carefully managed and cleaned up using appropriate methods. Always consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.