Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate | CAS No. 866775-17-9

Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate

Basic Information

CAS Number

866775-17-9

Molecular Formula

C8H7F3N2O2

Molecular Weight

220.15 g/mol

AD

Basic Physical Properties

COC(=O)c1ncc(cc1N)C(F)(F)F

InChI

InChI=1S/C8H7F3N2O2/c1-15-7(14)6-5(12)2-4(3-13-6)8(9,10)11/h2-3H,12H2,1H3

InChIKey

RPBPQAHDCODVNJ-UHFFFAOYSA-N

LogP

1.4692

Topological Polar Surface Area

65.21 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Synonyms & References

English

  • Methyl 3-amino-5-(trifluoromethyl)pyridine-2-carboxylate
  • SureCN2373041
  • 3-amino-5-trifluoromethyl-pyridine-2-carboxylic acid methyl ester
  • 2-Pyridinecarboxylic acid, 3-amino-5-(trifluoromethyl)-, methyl ester
  • AGN-PC-0COA5C
  • METHYL 3-AMINO-5-(TRIFLUOROMETHYL)PICOLINATE
  • 3-amino-5-trifluoromethyl-picolinic acid methyl ester

MDL Number

MFCD18259060

FAQ

What are the physical and chemical properties of Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate (CAS: 866775-17-9)?

Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate is a crystalline compound with a molecular weight of approximately 263.07 g/mol. It has moderate solubility in common organic solvents such as ethanol and acetone. The compound is relatively stable but can react with strong bases. It is important to store it in a cool, dry place away from direct sunlight.

How is Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate (CAS: 866775-17-9) typically synthesized?

Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate is typically synthesized through a multi-step process involving the reaction of trifluoromethylated pyridine with a carboxylic acid derivative. The synthesis usually involves the use of mild base catalysts to enhance selectivity and yield. Further purification techniques such as recrystallization or chromatography may be required.

What industries use Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate (CAS: 866775-17-9)?

Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drug candidates. It also finds applications in the polymer industry for developing novel materials with specific properties. Additionally, it may be used in the production of sensors and semiconductors due to its unique chemical structure.

What precautions should be taken when handling Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate (CAS: 866775-17-9)?

When handling Methyl 3-amino-5-(trifluoromethyl)-2-pyridinecarboxylate, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Handle in a well-ventilated area or a fume hood. Avoid skin contact and inhalation. In case of spill, clean up immediately using appropriate absorbent materials. Refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...