1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1) | CAS No. 86483-48-9
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1)
Basic Information
CAS Number
86483-48-9
Molecular Formula
C17H19ClFN3O3
Molecular Weight
367.81 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
>300 °C
Synonyms & References
English
- Ciprofloxacin hydrochloride
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochloride
- Ciflox
- Ciprofloxacin base
- CIPROFLOXACIN HCL
- CIPROFLOXACIN HCL HYDRATE
- CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATE
- Ciprofloxacin Monohydrochloride
- ciprofloxacine hydrochloride
- Ciproxan
- HCL
MDL Number
MFCD00079044
Customs Code
29419000
FAQ
What are the physical and chemical properties of 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 86483-48-9)?
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride is a crystalline solid with a molecular weight of approximately 414.93 g/mol. It has a pKa of about 4.2 and is soluble in water. The compound is stable under normal laboratory conditions but reacts with strong bases. It has poor solubility in organic solvents like hexane and ethyl acetate, but is well-soluble in polar solvents such as methanol and ethanol.
How is 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 86483-48-9) typically synthesized?
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride is synthesized via condensation of 6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid with cyclopropyl chloride in the presence of a base such as triethylamine. The reaction is carried out in acetonitrile at room temperature, with high selectivity and yield. The intermediate is then converted to the hydrochloride salt using hydrogen chloride gas.
What industries use 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 86483-48-9)?
1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride is used in the pharmaceutical industry for developing new antipsychotic drugs. It is also explored for its potential in sensor technology and semiconductor applications due to its unique chemical structure and properties.
What precautions should be taken when handling 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (CAS: 86483-48-9)?
When handling 1-Cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a well-ventilated area and use a fume hood during handling to minimize exposure to vapors. In case of a spill, contain the spill using absorbent material and dispose of it according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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