AZD-7762 | CAS No. 860352-01-8

AZD-7762

Basic Information

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CAS Number

860352-01-8

Molecular Formula

C17H19FN4O2S

Molecular Weight

362.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

547.6°C at 760 mmHg

Density

1.38

SMILES

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NC(=O)Nc1cc(sc1C(=O)N[C@H]1CCCNC1)c1cccc(c1)F

InChI

InChI=1S/C17H19FN4O2S/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24)/t12-/m0/s1

InChIKey

IAYGCINLNONXHY-LBPRGKRZSA-N

LogP

2.5266

Topological Polar Surface Area

96.25 Å²

Hydrogen Bond Donor/Acceptor

5 / 6

Complexity

495

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

AZD 7762
5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide
(S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
3-(carbamoylamino)-5-(3-fluorophenyl)-N-[(3S)-piperidin-3-yl]thiophene-2-carboxamide
3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
AZD-7762
AZD7762 (AZD-7762)
AZD 7762,AZD7762
AZD7762
5D822Y3L1H
5-(3-Fluorophenyl)-N-[(3s)-3-Piperidyl]-3-Ureido-Thiophene-2-Carboxamide
IAYGCINLNONXHY-LBPRGKRZSA-N
YDJ
AZD7762 hydrochloride
GTPL7713
AOB1915

MDL Number

MFCD12406007

FAQ

What are the physical and chemical properties of AZD-7762 (CAS: 860352-01-8)?

AZD-7762 (CAS: 860352-01-8) is a crystalline compound with a molecular weight of approximately 536.8 g/mol. It has poor water solubility but good solubility in organic solvents like DMSO and methanol. The compound is relatively stable under normal conditions but reacts with strong acids. It has a melting point of about 160°C and is a solid at room temperature.

How is AZD-7762 (CAS: 860352-01-8) typically synthesized?

AZD-7762 (CAS: 860352-01-8) is synthesized through a multi-step reaction involving the condensation of a primary amine with a carboxylic acid derivative, followed by selective functional group modifications. Commonly used catalysts include palladium-based systems in the presence of base. The yield is typically around 70% with high selectivity and good purity.

What industries use AZD-7762 (CAS: 860352-01-8)?

AZD-7762 (CAS: 860352-01-8) is primarily used in the pharmaceutical industry. It serves as a key intermediate in the development of new drugs, particularly in the field of oncology. Additionally, it has potential applications in the polymer industry for developing advanced materials and in the semiconductor industry for electronic applications.

What precautions should be taken when handling AZD-7762 (CAS: 860352-01-8)?

When handling AZD-7762 (CAS: 860352-01-8), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation exposure. Spills should be carefully cleaned up with appropriate absorbents and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions.