Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate | CAS No. 85418-82-2
Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate
Basic Information
CAS Number
85418-82-2
Molecular Formula
C13H13NO3
Molecular Weight
231.25 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
368.7°C at 760 mmHg
Density
1.214
Flash Point
176.8°C
Refractive Index
1.563
Synonyms & References
English
- Ethyl 4-hydroxy-6-methylquinoline-3-carboxylate
- 3-Quinolinecarboxylicacid, 4-hydroxy-6-methyl-, ethyl ester
- 4-HYDROXY-6-METHYL-QUINOLINE-3-CARBOXYLIC ACID ETHYL ESTER
- 4-Hydroxy-6-methylquinoline-3-carboxylic acid ethyl ester
- 3-carbethoxy-6-methyl-1,4-dihydro-4-oxoquinoline
- ETHYL 4-HYDROXY-6-METHYL-3-QUINOLINECARBOXYLATE
- ethyl 6-methyl-4-oxo-1,4-dihydroquinolin-3-carboxylate
- ethyl 6-methyl-4-quinolone-3-carboxylate
MDL Number
MFCD00087702
Customs Code
2933499090
FAQ
What are the physical and chemical properties of Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2)?
Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) is a crystalline compound with a molecular weight of approximately 242.23 g/mol. It has a low solubility in water (2.5 g/100 mL at 20°C) and higher solubility in organic solvents like ethanol and acetone. The compound is reactive towards bases and can undergo hydrolysis. It is not flammable but may react with strong oxidizing agents.
How is Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) typically synthesized?
Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) can be synthesized by the condensation of 4-hydroxy-6-methyl-3-quinolinecarboxylic acid with ethylamine followed by esterification. The reaction is typically carried out in the presence of a catalyst like hydrochloric acid to promote the esterification step. The yield is around 75-80% with good selectivity.
What industries use Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2)?
Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) is used in the pharmaceutical industry for the synthesis of certain drug candidates, particularly those involving quinoline derivatives. It also has applications in the polymer industry for modifying the properties of polymers and in the development of sensors and semiconductors due to its unique chemical structure.
What precautions should be taken when handling Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2)?
When handling Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbent materials and the area should be washed down with water. Always consult the Safety Data Sheet (SDS) for specific guidance on handling and storage.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
