Compound Q&A

How is Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) typically synthesized?

Answer

Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate
Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate (CAS: 85418-82-2) can be synthesized by the condensation of 4-hydroxy-6-methyl-3-quinolinecarboxylic acid with ethylamine followed by esterification. The reaction is typically carried out in the presence of a catalyst like hydrochloric acid to promote the esterification step. The yield is around 75-80% with good selectivity.

About

CAS No 85418-82-2
English Name Ethyl 4-hydroxy-6-methyl-3-quinolinecarboxylate
Molecular Formula C13H13NO3
Molecular Weight 231.25 g/mol
SMILES CCOC(=O)c1cnc2ccc(cc2c1O)C
InChIKey WRHXUGRUTJJRQQ-UHFFFAOYSA-N
Last Updated: 2026-01-13 10:36

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