N-(2-Nitrophenyl)methanesulfonamide

Basic Information

View in Editor

CAS Number

85150-03-4

Molecular Formula

C7H8N2O4S

Molecular Weight

216.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

View in Editor

CS(=O)(=O)NC1=CC=CC=C1[N+](=O)[O-]

InChI

InChI=1S/C7H8N2O4S/c1-14(12,13)8-6-4-2-3-5-7(6)9(10)11/h2-5,8H,1H3

InChIKey

WFRCGQPFZHHIDL-UHFFFAOYSA-N

LogP

2.64330

Complexity

303

Synonyms & References

English

AC6943
NSC166614
FT-0766698
CS-0206934
WFRCGQPFZHHIDL-UHFFFAOYSA-N
MFCD00464153
SCHEMBL1039965
BS-29606
N-(2-nitrophenyl)methanesulfonamide
SY016706
AKOS003853028
SB77090
DTXSID70304643
85150-03-4
NSC-166614
Methanesulfonamide,N-(2-nitrophenyl)-
N-(2-NITROPHENYL)METHANESULFONAMIDE
2'-nitro-methane-sulfonanilide
N-methanesulfonyl-2-nitroaniline

MDL Number

MFCD00464153

Customs Code

2935009090

FAQ

What are the physical and chemical properties of N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4)?

N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4) is a white crystalline powder with a molecular weight of approximately 219.13 g/mol. It has a low solubility in water but good solubility in organic solvents like methanol and acetonitrile. This compound is relatively stable under normal conditions but exhibits reactivity towards strong bases and reducing agents.

How is N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4) typically synthesized?

N-(2-Nitrophenyl)methanesulfonamide is typically synthesized by the reaction of 2-nitrophenol with methanesulfonyl chloride in the presence of a base such as triethylamine. The reaction yields a high purity product with good selectivity and a yield of around 80-90%. This method requires gentle heating and is usually performed under an inert atmosphere.

What industries use N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4)?

N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds, including drugs. It is also utilized in the polymer industry for modifying polymers and in the sensor industry for developing chemical sensors. Additionally, it has applications in the semiconductor industry for use in organic electronics and materials.

What precautions should be taken when handling N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4)?

When handling N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS) guidelines. Proper storage in a cool, dry place away from incompatible materials is recommended. Always refer to the latest SDS for detailed safety information.