N-(2-Nitrophenyl)methanesulfonamide(CAS: 85150-03-4)

N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4) is a white crystalline powder with a molecular weight of approximately 219.13 g/mol. It has a low solubility in water but good solubility in organic solvents like methanol and acetonitrile. This compound is relatively stable under normal conditions but exhibits reactivity towards strong bases and reducing agents.

N-(2-Nitrophenyl)methanesulfonamide is typically synthesized by the reaction of 2-nitrophenol with methanesulfonyl chloride in the presence of a base such as triethylamine. The reaction yields a high purity product with good selectivity and a yield of around 80-90%. This method requires gentle heating and is usually performed under an inert atmosphere.

N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds, including drugs. It is also utilized in the polymer industry for modifying polymers and in the sensor industry for developing chemical sensors. Additionally, it has applications in the semiconductor industry for use in organic electronics and materials.

When handling N-(2-Nitrophenyl)methanesulfonamide (CAS: 85150-03-4), it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up according to the Material Safety Data Sheet (MSDS) guidelines. Proper storage in a cool, dry place away from incompatible materials is recommended. Always refer to the latest SDS for detailed safety information.