(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine | CAS No. 849924-74-9

(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine

Basic Information

CAS Number

849924-74-9

Molecular Formula

C34H32FeO2P2

Molecular Weight

590.41 g/mol

AD

Basic Physical Properties

[CH]1[CH][CH][CH][CH]1.C[C@@H]([C]1[CH][CH][CH][C]1P(c1ccco1)c1ccco1)P(c1ccccc1C)c1ccccc1C.[Fe]

InChI

InChI=1S/C29H27O2P2.C5H5.Fe/c1-21-11-4-6-14-25(21)32(26-15-7-5-12-22(26)2)23(3)24-13-8-16-27(24)33(28-17-9-19-30-28)29-18-10-20-31-29;1-2-4-5-3-1;/h4-20,23H,1-3H3;1-5H;/t23-;;/m0../s1

InChIKey

SPAUEXSFJREZBQ-IFUPQEAVSA-N

LogP

7.195440000000008

Topological Polar Surface Area

26.28 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Synonyms & References

English

  • s-funan-2-meph
  • (S)-1-[(R)-2-[Di(2-furyl)phosphino]ferrocenyl]ethyldi-otolylphosphine
  • (2S)-1-[(1S)-1-[BIS(2-METHYLPHENYL)PHOSPHINO]ETHYL]-2-(DI-2-FURANYLPHOSPHINO)FERROCENE
  • (s,s)-1-{1-[bis(2-methylphenyl)phosphino]ethyl}-2-[di(2-furyl)phosphino]ferrocene (acc to cas)
  • (S)-1-[(R)-2-(Di-2-furylphosphino)ferrocenyl]-ethyl-di-(2-methylphenyl)phosphine
  • (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-Methylphenyl)phosphine
  • (2S)-1-[(1S)-1-[BIS(2-METHYL
  • (S)-1-{(S)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine
  • [(1S)-1-[2-[bis(furan-2-yl)phosphanyl]cyclopenta-2,4-dien-1-yl]ethyl]-bis(2-methylphenyl)phosphane,cyclopenta-1,3-diene,iron(2+)
  • [(1S)-1-[2-[bis(furan-2-yl)phosphanyl]cyclopenta-2,4-dien-1-yl]ethyl]-bis(2-methylphenyl)phosphane
  • cyclopenta-1,3-diene
  • iron(2+)
  • Josiphos SL-J452-2

MDL Number

MFCD08561169

Customs Code

29321900

FAQ

What are the physical and chemical properties of (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine (CAS: 849924-74-9)?

This compound is a chiral phosphine ligand. It has a crystalline form with a molecular weight of approximately 713.5 g/mol. It is poorly water-soluble but soluble in organic solvents such as dichloromethane and toluene. The compound is known for its reactivity in palladium-catalyzed cross-coupling reactions and its stability in air and moisture.

How is (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine (CAS: 849924-74-9) typically synthesized?

This compound is typically synthesized using a multistep process involving the preparation of ferrocene derivatives and subsequent phosphination reactions. Key steps include the formation of the 2-[di(2-furyl)phosphino]ferrocenyl] group followed by coupling with bis(2-methylphenyl)phosphine. This process requires the use of various catalysts and solvents, and the yield can be influenced by the purity of reactants and reaction conditions.

What industries use (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine (CAS: 849924-74-9)?

This compound is primarily used in the pharmaceutical and polymer industries for its catalytic properties. It is particularly useful in the synthesis of chiral molecules and in the preparation of polymers with specific properties. It also finds application in sensors and semiconductors due to its electronic and optical properties.

What precautions should be taken when handling (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine (CAS: 849924-74-9)?

When handling this compound, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be well-ventilated. Safety data sheets (SDS) should be consulted for specific handling and disposal instructions.

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