(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine | CAS No. 849924-42-1

(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine

Basic Information

CAS Number

849924-42-1

Molecular Formula

C28H37FeO2P2

Molecular Weight

523.38 g/mol

AD

Basic Physical Properties

C1[CH][CH][CH][CH]1.C[C@H](P(C(C)(C)C)C(C)(C)C)[C]1[CH][CH][CH][C]1P(c1ccco1)c1ccco1.[Fe]

InChI

InChI=1S/C23H31O2P2.C5H6.Fe/c1-17(27(22(2,3)4)23(5,6)7)18-11-8-12-19(18)26(20-13-9-15-24-20)21-14-10-16-25-21;1-2-4-5-3-1;/h8-17H,1-7H3;1-4H,5H2;/t17-;;/m0../s1

InChIKey

RIAXEXRSCMFFRW-RMRYJAPISA-N

LogP

7.710410000000008

Topological Polar Surface Area

26.28 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

213

Synonyms & References

English

  • 1,2,3,4,5-cyclopentanepentayl, compd. with 1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(di-2-furanylphosphino)-1,2,3,4,5-cyclopentanepentayl, iron salt (1:1:1)
  • (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine
  • (3S,4S)-tert-butyl 3,4-dihydroxypyrrolidine-1-carboxylate
  • tert-butyl (3S,4S)-3,4-dihydroxypyrrolidine-1-carboxylate
  • (3S,4S)-1-Boc-pyrrolidine-3,4-diol
  • tert-butyl (3R,4R)-3,4-dihydroxypyrrolidine-1-carboxylate
  • 1-Pyrrolidinecarboxylic acid, 3,4-dihydroxy-, 1,1-dimethylethyl ester,(3S,4S)-
  • (3S,4S)-1-Boc-dihydroxypyrrolidine
  • SB10906
  • trans-tert-Butyl 3,4-dihydroxypyrrolidine-1-carbo

MDL Number

MFCD08561159

FAQ

What are the physical and chemical properties of (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-42-1)?

The compound has a crystalline form with a molecular weight of approximately 652.5 g/mol. It is poorly soluble in water but has good solubility in organic solvents. The compound is known for its high reactivity, particularly in coordination chemistry applications. It exhibits Lewis basic properties and can serve as a ligand in transition metal complexes.

How is (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-42-1) typically synthesized?

This compound is typically synthesized through the coupling of ferrocene derivatives with di-tert-butylphosphine. The reaction involves the use of a palladium catalyst, a phase transfer catalyst, and a base. The method ensures high selectivity and yield, making it suitable for the preparation of chiral ligands in asymmetric catalysis.

What industries use (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-42-1)?

This compound is primarily used in the pharmaceutical industry for its chiral ligand properties, aiding in the synthesis of enantiopure compounds. It is also found in the polymer industry for catalytic applications, and in the semiconductor industry for its use in metalorganic chemical vapor deposition (MOCVD) processes.

What precautions should be taken when handling (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-42-1)?

Proper safety equipment, including gloves, safety goggles, and a lab coat, should be worn when handling this compound. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and the compound should be stored in a cool, dry place away from oxidizing agents. Always consult a Safety Data Sheet (SDS) for detailed handling and safety information.

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