(4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid

Basic Information

View in Editor

CAS Number

84793-07-7

Molecular Formula

C24H27NO6

Molecular Weight

425.48 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

105-113°C

Boiling Point

638.1℃ at 760 mmHg

Refractive Index

1.57

Specific Rotation

-8.0° - -12.0° (c=1, CH3COOH)

SMILES

View in Editor

CC(C)(C)OC(=O)[C@H](CCC(=O)O)NC(=O)OCC1c2ccccc2-c3ccccc13

InChI

InChI=1S/C24H27NO6/c1-24(2,3)31-22(28)20(12-13-21(26)27)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,27)/t20-/m0/s1

InChIKey

GOPWHXPXSPIIQZ-FQEVSTJZSA-N

LogP

4.100200000000002

Topological Polar Surface Area

101.93000000000002 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Complexity

635

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Fmoc-L-Glutamic acid 1-tert-butyl ester
N-(9-Fluorenylmethoxycarbonyl)glutamic acid α-tert-butyl ester
(4S)-4-(9H-fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
FMOC-GLU-OBUT
Fmoc-Glu-OtBu
Fmoc-L-Glu-OtBu
Fmoc-L-glutamic acid α-tert.butyl ester
N-Fmoc-L-glutamic acid 1-tert-butyl ester
Fmoc-L-Glu-O-t-Bu
Fmoc-Glu-O-t-Bu
Fmoc-Glu(OBut)-OH
(S)-4-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-tert-butoxy-5-oxopentanoic acid
Fmoc-Glu-Ot-Bu
PubChem10014
KSC448A0B
GOPWHXPXSPIIQZ-FQEVSTJZSA-N
BCP26020
C

MDL Number

MFCD00065648

Customs Code

29224290

FAQ

What is (4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid (CAS: 84793-07-7)?

This compound is a complex organic molecule with the CAS number 84793-07-7. It features a pentanoic acid backbone with a 5-oxo group, an amino group protected by a fluoren-9-ylmethoxy carbonyl (Fmoc) moiety, and a tert-butyl ether substituent. Its stereochemistry is defined by the (4S) configuration, making it a key intermediate in pharmaceutical synthesis and molecular research. The structure combines aromatic, aliphatic, and functional groups, contributing to its reactivity and utility in chemical processes.

What are the main uses of (4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid (CAS: 84793-07-7)?

This compound is primarily used in pharmaceutical research as a protected amino acid derivative, enabling controlled functionalization in drug molecule synthesis. It serves as an intermediate in the development of bioactive compounds and is also employed in organic chemistry for structural studies. Its unique Fmoc group and tert-butyl protection make it valuable in peptide chemistry and advanced chemical applications.

Is (4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid (CAS: 84793-07-7) safe?

Safety data for this compound is limited, but as a chemical reagent, it requires standard laboratory precautions. It may pose mild irritation risks upon contact with skin or eyes, and inhalation should be avoided. Always handle it with gloves, safety goggles, and in a well-ventilated area. Adherence to OSHA and EPA guidelines is recommended for safe use and disposal.

How should (4S)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-5-[(2-methyl-2-propanyl)oxy]-5-oxopentanoic acid (CAS: 84793-07-7) be stored?

Store this compound in a cool, dry place (ideally below 25°C), away from light, and in airtight containers to prevent moisture absorption. Ensure it is kept in a chemically inert environment to maintain stability. Avoid exposure to strong oxidizers or incompatible substances. Regularly check storage conditions to preserve its integrity and prolong shelf life.