4-Nitro-1H-pyrrolo[2,3-b]pyridine

Basic Information

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CAS Number

83683-82-3

Molecular Formula

C7H5N3O2

Molecular Weight

163.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Density

1.58

Refractive Index

1.74

SMILES

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[O-][N+](=O)c1ccnc2c1cc[nH]2

InChI

InChI=1S/C7H5N3O2/c11-10(12)6-2-4-9-7-5(6)1-3-8-7/h1-4H,(H,8,9)

InChIKey

ULDUNXDRDOJMJZ-UHFFFAOYSA-N

LogP

1.99430

Complexity

192

Synonyms & References

English

4-Nitro-7-azaindole
1H-Pyrrolo[2,3-b] pyridine, 4-nitro-
4-nitro-1H-pyrrolo[2,3-b]pyridine
4-nitro-1H-pyrrolo<2,3-b>pyridine
4-Niro-1H-pyrrolo[2,3-b]pyridine
1H-PYRROLO[2,3-B]PYRIDINE, 4-NITRO-
PubChem24132
ULDUNXDRDOJMJZ-UHFFFAOYSA-N
BCP05409
STL557654
FCH856902
BBL103844
PB17435
OR301264
AB0026917
ST1090518
AX8058967
AM20061530
W8673
A2

MDL Number

MFCD07778365

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3)?

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is a crystalline solid with a molecular weight of approximately 229.07 g/mol. It is slightly soluble in water and more soluble in organic solvents like dichloromethane and ethanol. It exhibits moderate reactivity towards nucleophiles and can undergo substitution reactions. The compound is stable under normal conditions but should be handled with care to avoid prolonged contact with skin and inhalation of dust.

How is 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) typically synthesized?

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is commonly synthesized by the nitration of 1H-pyrrolo[2,3-b]pyridine with nitric acid in the presence of sulfuric acid as a catalyst. The reaction proceeds under controlled conditions to achieve high selectivity and yield, typically around 80-90%.

What industries use 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3)?

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is used in the pharmaceutical and chemical manufacturing industries for its potential applications in drug synthesis and as a precursor for other compounds. It is also explored in sensor technology and semiconductor manufacturing for its unique electronic properties.

What precautions should be taken when handling 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3)?

When handling 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to avoid inhalation of dust or fumes. Spills should be handled with caution, and the material safety data sheet (MSDS) should be consulted for specific spill procedures. Proper storage in a cool, dry place away from sources of heat and ignition is also crucial.