4-Nitro-1H-pyrrolo[2,3-b]pyridine(CAS: 83683-82-3)

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is a crystalline solid with a molecular weight of approximately 229.07 g/mol. It is slightly soluble in water and more soluble in organic solvents like dichloromethane and ethanol. It exhibits moderate reactivity towards nucleophiles and can undergo substitution reactions. The compound is stable under normal conditions but should be handled with care to avoid prolonged contact with skin and inhalation of dust.

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is commonly synthesized by the nitration of 1H-pyrrolo[2,3-b]pyridine with nitric acid in the presence of sulfuric acid as a catalyst. The reaction proceeds under controlled conditions to achieve high selectivity and yield, typically around 80-90%.

4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3) is used in the pharmaceutical and chemical manufacturing industries for its potential applications in drug synthesis and as a precursor for other compounds. It is also explored in sensor technology and semiconductor manufacturing for its unique electronic properties.

When handling 4-Nitro-1H-pyrrolo[2,3-b]pyridine (CAS: 83683-82-3), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The substance should be used in a well-ventilated area or a fume hood to avoid inhalation of dust or fumes. Spills should be handled with caution, and the material safety data sheet (MSDS) should be consulted for specific spill procedures. Proper storage in a cool, dry place away from sources of heat and ignition is also crucial.