(3R)-3-Amino-3-phenylpropanoic acid hydrochloride (1:1)

Basic Information

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CAS Number

83649-48-3

Molecular Formula

C9H12ClNO2

Molecular Weight

201.65 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

163-180 ºC

SMILES

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C1=CC=C(C=C1)C(CC(=O)O)N.Cl

InChI

InChI=1S/C9H11NO2.ClH/c10-8(6-9(11)12)7-4-2-1-3-5-7;/h1-5,8H,6,10H2,(H,11,12);1H/t8-;/m1./s1

InChIKey

ABEBCTCOPRULFS-DDWIOCJRSA-N

LogP

1.5829

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

153

Safety Information

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Sensitiveness

Air Sensitive

Synonyms & References

English

SCHEMBL4150999
ABEBCTCOPRULFS-DDWIOCJRSA-N
MFCD03092946
(R)-beta-Homophenylglycine hydrochloride
(R)-3-amino-3-phenyl-propionic acid HCl salt
(R)-3-Amino-3-phenylpropanoicAcidHydrochloride
H-Phg-(C#CH2)OH.HCl
AC-5692
(R)-3-Amino-3-phenylpropionic acid, HCl
(3R)-3-amino-3-phenylpropanoic acid hydrochloride
83649-48-3
(R)-3-Amino-3-phenylpropionic acid hydrochloride
(R)-3-amino-3-phenylpropanoic acid hydrochloride
Z1696091779
(3R)-3-amino-3-phenylpropanoic acid;hydrochloride
(R)-3-AMINO-3-PHENYLPROPANOIC ACID HCL
AKOS015889476
DS-16757
EN300-70588
J-502208
(R)-3-Amino-3-phenylpropanoic acid hydrochloride
(R)-3-Amino-3-phenylpropionicacid hydrochloride
L-BETA-HOMOPHENYLGLYCINE HYDROCHLORIDE
H-PHG(C*CH2)OH HCL
H-D-BETA-PHE-OH
D-BETA-PHENYLALANINE
(R)-3-AMINO-3-PHENYLPROPANOIC ACID
(R)-(-)-3-AMINO-3-PHENYLPROPIONIC ACID HYDROCHLORIDE
(R)-3-AMINO-3-PHENYLPROPIONIC ACID
D-(-)-3-Amino-3-phenylpropionic acid
R-3-Amino-3-phenyl-propionic acid

MDL Number

MFCD03092946

Customs Code

2922499990

FAQ

What are the physical and chemical properties of (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (CAS: 83649-48-3)?

(3R)-3-Amino-3-phenylpropanoic acid hydrochloride is a crystalline solid with a molecular weight of approximately 220.31 g/mol. It has a solubility of about 40 mg/mL in water. The compound is mildly reactive, particularly in acidic and basic conditions, making it susceptible to hydrolysis and racemization. It is a key intermediate in the synthesis of various pharmaceuticals and agrochemicals.

How is (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (CAS: 83649-48-3) typically synthesized?

(3R)-3-Amino-3-phenylpropanoic acid hydrochloride is typically synthesized through the coupling of an amino acid and a phenyl propanoic acid derivative. Common methods include esterification followed by nucleophilic substitution, using reagents like hydrogen chloride in acetic acid. The reaction yields are generally high, with good control over the stereochemistry at the chiral center.

What industries use (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (CAS: 83649-48-3)?

(3R)-3-Amino-3-phenylpropanoic acid hydrochloride finds application in the pharmaceutical industry as a precursor for the synthesis of various drugs. It is also used in the development of agrochemicals and in the production of certain sensors due to its unique chemical properties and reactivity.

What precautions should be taken when handling (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (CAS: 83649-48-3)?

When handling (3R)-3-Amino-3-phenylpropanoic acid hydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Use a fume hood to minimize exposure to airborne particles. Spills should be cleaned up carefully, using appropriate absorbents, and the area should be flushed with water. Always consult the safety data sheet (SDS) for specific handling and disposal instructions.