Compound Q&A

How is (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (CAS: 83649-48-3) typically synthesized?

Answer

(3R)-3-Amino-3-phenylpropanoic acid hydrochloride (1:1)
(3R)-3-Amino-3-phenylpropanoic acid hydrochloride is typically synthesized through the coupling of an amino acid and a phenyl propanoic acid derivative. Common methods include esterification followed by nucleophilic substitution, using reagents like hydrogen chloride in acetic acid. The reaction yields are generally high, with good control over the stereochemistry at the chiral center.

About

CAS No 83649-48-3
English Name (3R)-3-Amino-3-phenylpropanoic acid hydrochloride (1:1)
Molecular Formula C9H12ClNO2
Molecular Weight 201.65 g/mol
SMILES C1=CC=C(C=C1)C(CC(=O)O)N.Cl
InChIKey ABEBCTCOPRULFS-DDWIOCJRSA-N
Last Updated: 2025-10-13 11:18

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