Methyl (4-aminophenyl)acetate hydrochloride (1:1) | CAS No. 83528-16-9
Methyl (4-aminophenyl)acetate hydrochloride (1:1)
Basic Information
CAS Number
83528-16-9
Molecular Formula
C9H12ClNO2
Molecular Weight
201.65 g/mol
AD
Chemical Classification
Basic Physical Properties
Physical State
Pale-yellow to Yellow-brown Solid
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- SB77847
- DTXSID80512939
- MFCD06796526
- Methyl2-(4-aminophenyl)acetatehydrochloride
- SCHEMBL6801556
- (4-amino-phenyl)-acetic acid methyl ester hydrochloride
- methyl 4-aminophenylacetate hydrochloride
- A13982
- EN300-28630
- (4-Amino-phenyl)-acetic acid methyl ester HCl
- CS-0172520
- WRZBLDDHUMBLKP-UHFFFAOYSA-N
- Methyl (4-aminophenyl)acetate--hydrogen chloride (1/1)
- 4-amino-benzeneacetic acid methyl ester hcl
- 83528-16-9
- methyl 2-(4-aminophenyl)acetate hydrochloride
- Z285139238
- (4-amino-phenyl)-aceticacidmethylesterhydrochloride
- methyl 2-(4-aminophenyl)acetate;hydrochloride
- AKOS015995790
- AS-35409
- Methyl 2-(4-aminophenyl)acetate hydrochloride
- Benzeneacetic acid,4-amino-, methyl ester, hydrochloride (1:1)
- methyl (p-aminophenyl)acetate hydrochloride
- Methyl 4-aminophenylacetate hydrochloride
MDL Number
MFCD06796526
FAQ
What are the physical and chemical properties of Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9)?
Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9) is a white crystalline solid with a molecular weight of approximately 229.77 g/mol. It has a pKa of around 2.3. The compound is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. It is stable under normal conditions but should be stored in a dry place to prevent hydrolysis. Reactivity is moderate, and it is typically used in pharmaceutical and chemical applications due to its stability and reactivity.
How is Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9) typically synthesized?
Methyl (4-aminophenyl)acetate hydrochloride can be synthesized through a multi-step process. Initially, 4-aminophenol is esterified with acetic anhydride to form methyl (4-aminophenyl)acetate, which is then treated with hydrochloric acid. This process requires careful temperature control and can be optimized with the use of a catalyst like p-Toluenesulfonic acid. The yield is typically around 85-90%, and the final product is isolated by recrystallization.
What industries use Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9)?
Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9) is primarily used in the pharmaceutical industry for the synthesis of various drugs. It is also utilized in the production of electronic materials, specifically in the manufacturing of semiconductors due to its ability to form stable derivatives. Additionally, it can be used in the polymer industry as an intermediate for functional materials and in the development of new sensor technologies.
What precautions should be taken when handling Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9)?
When handling Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation of vapors. Spills should be cleaned up immediately using appropriate absorbent materials. In case of skin contact, wash with plenty of water. For eye contact, flush with water for at least 15 minutes. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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