How is Methyl (4-aminophenyl)acetate hydrochloride (CAS: 83528-16-9) typically synthesized?

Methyl (4-aminophenyl)acetate hydrochloride can be synthesized through a multi-step process. Initially, 4-aminophenol is esterified with acetic anhydride to form methyl (4-aminophenyl)acetate, which is then treated with hydrochloric acid. This process requires careful temperature control and can be optimized with the use of a catalyst like p-Toluenesulfonic acid. The yield is typically around 85-90%, and the final product is isolated by recrystallization.