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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine | CAS No. 832114-09-7

1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine

Basic Information

Chemical_Structure_Of
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CAS Number

832114-09-7

Molecular Formula

C16H26BN3O2

Molecular Weight

303.22 g/mol

AD

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds
Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

125.0-125.7°C

SMILES

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CN1CCN(CC1)c2cc(ccn2)B3OC(C)(C)C(C)(C)O3

InChI

InChI=1S/C16H26BN3O2/c1-15(2)16(3,4)22-17(21-15)13-6-7-18-14(12-13)20-10-8-19(5)9-11-20/h6-7,12H,8-11H2,1-5H3

InChIKey

CERIBIOLVVNLDM-UHFFFAOYSA-N

LogP

1.1325999999999996

Topological Polar Surface Area

37.83 Ų

Hydrogen Bond Donor/Acceptor

0 / 5

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazine
  • 1-Methyl-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxa-borolan-2-yl)pyridin-2-yl)piperazine
  • 1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine
  • 1-METHYL-5-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-2-YL]PIPERAZINE
  • 2-(4-Methylpiperazin-1-yl)pyridine-4-boronic acid
  • 2-(4-METHYLPIPERAZIN-1-YL)PYRIDINE-5-BORONIC ACID PINACOL ESTER
  • 2-(4-Methylpiperazino)pyridine-4-boronic acid pinacol ester
  • Piperazine,1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-
  • 1-methyl-4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-piperazine
  • 1-methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine
  • 1-Methyl-4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine
  • 2-(2?HYDROXY-5?METHYLPHENYL)-BENZOTRIAZOLE
  • 2-(4-Methylpiperazin-1-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
  • 2-(4-methylpiperazin-1-yl)pyridine-4-boronic acid,pinacol ester
  • 1-methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]piperazine

MDL Number

MFCD05864305

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine (CAS: 832114-09-7)?
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine is a white crystalline solid with a molecular weight of approximately 422.4 g/mol. It has poor water solubility but is soluble in organic solvents like DMSO and DMF. This compound reacts with nucleophiles via its boron atom. It is stable under normal conditions but should be handled with care to avoid decomposition.

How is 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine (CAS: 832114-09-7) typically synthesized?
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine is synthesized via the Suzuki coupling reaction, where 1-methyl-4-pyridinylpiperazine is reacted with 4,4,5,5-tetramethyl-2-borono-1,3,2-dioxaborolane in the presence of a palladium catalyst and base. The reaction conditions typically include Pd(PPh3)4 as the catalyst and Na2CO3 as the base. The yield is generally high, and the product is isolated by column chromatography.

What industries use 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine (CAS: 832114-09-7)?
1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine is used in the pharmaceutical industry for its potential as a drug candidate. It is also explored in the polymer industry for synthesizing new materials. Additionally, it has applications in sensor technology and semiconductor manufacturing due to its chemical reactivity and structural properties.

What precautions should be taken when handling 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine (CAS: 832114-09-7)?
When handling 1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine, ensure proper personal protective equipment (PPE) usage, including gloves, safety glasses, and a lab coat. Store it in a dry, well-ventilated area and use a fume hood during preparation. Spills should be promptly cleaned up with appropriate absorbent materials. Consult the Safety Data Sheet (SDS) for detailed safety information and emergency response procedures.

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Supplier Information

1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — Shanghai Yuyeh Biotechnology Co., Ltd.

Shanghai Yuyeh Biotechnology Co., Ltd.

CAS Number: 832114-09-7

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Ningbo Kunjue Medicine Technology Co., Ltd.

CAS Number: 832114-09-7

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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu

ShangHaiYiJiShengWuKeJiYouXianGongSiXiaoShouBu

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ShangHaiKaiSen Biotechnology Co Ltd

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HuBeiGuoYunFuRui Technology Co Ltd

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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — HePeng （ ShangHai ） Biotechnology Co Ltd

HePeng （ ShangHai ） Biotechnology Co Ltd

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Shanghai Hansi Chemical Co., Ltd.

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JiangSuBeiDaYiYao Technology Co Ltd

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Shanghai Jieshukai Biotechnology Co., Ltd.

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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — JiangSuAiKangShengWuYiYaoYanFa Co Ltd

JiangSuAiKangShengWuYiYaoYanFa Co Ltd

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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — ShenZhenAiTaHuaXue Co Ltd

ShenZhenAiTaHuaXue Co Ltd

CAS Number: 832114-09-7

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1-Methyl-4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]piperazine — Jin Jinle (Hunan) Chemical Co., Ltd.

Jin Jinle (Hunan) Chemical Co., Ltd.

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Chongqing Zhisheng Technology Co., Ltd.

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Changzhou Tolly Chemical Co., Ltd.

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