7-Methoxy-4-quinolinol

Basic Information

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CAS Number

82121-05-9

Molecular Formula

C10H9NO2

Molecular Weight

175.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

285°C

Boiling Point

227.223ºC at 760 mmHg

Density

1.33g/cm3

Flash Point

91.222℃

Refractive Index

1.659

SMILES

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COC1=CC2=C(C=C1)C(=O)C=CN2

InChI

InChI=1S/C10H9NO2/c1-13-7-2-3-8-9(6-7)11-5-4-10(8)12/h2-6H,1H3,(H,11,12)

InChIKey

NQUPXNZWBGZRQX-UHFFFAOYSA-N

LogP

1.9489999999999996

Topological Polar Surface Area

42.35 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

237

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-Hydroxy-7-methoxyquinoline
AMY5433
7-methoxyquinolin-4-ol
PS-6049
MFCD11501414
190516-85-9
CS-W017458
4(1H)-Quinolinone, 7-methoxy-
SB67712
4-Hydroxy-7-methoxyquinoline, 97%
Oprea1_718401
A840253
4-hydroxy-7-methoxy-quinoline
AKOS006230117
AC-3264
Z381338442
7-Methoxyquinolin-4(1H)-one
CHEMBL163900
AKOS002683713
SY004730
SCHEMBL704734
SY276702
J-650316
7-methoxy-1H-quinolin-4-one
DTXSID701002480
7-Methoxy-4-quinolinol
AB04264
M1966
7-Methoxy-1H-4-quinolinone
7-Methoxy-quinolin-4-ol
FT-0618672

MDL Number

MFCD00169015

Customs Code

2933499090

FAQ

What are the physical and chemical properties of 7-Methoxy-4-quinolinol (CAS: 82121-05-9)?

7-Methoxy-4-quinolinol is a crystalline solid with a molecular weight of approximately 213.2 g/mol. It is poorly soluble in water but soluble in solvents like ethanol and dimethylformamide. The compound shows moderate reactivity and is stable under normal conditions. It is typically prepared in the solid state and can be used in various chemical reactions.

How is 7-Methoxy-4-quinolinol (CAS: 82121-05-9) typically synthesized?

7-Methoxy-4-quinolinol is commonly synthesized via the methylation of 4-quinolinol using methanol and a strong base like sodium hydride. The reaction proceeds in an aprotic solvent at low temperature, yielding a high purity product with good selectivity. The process typically involves careful handling of reactive intermediates and proper cooling to prevent side reactions.

What industries use 7-Methoxy-4-quinolinol (CAS: 82121-05-9)?

7-Methoxy-4-quinolinol is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds and in the production of certain dyes and pigments. It is also employed in the development of new materials for electronic and optoelectronic applications.

What precautions should be taken when handling 7-Methoxy-4-quinolinol (CAS: 82121-05-9)?

When handling 7-Methoxy-4-quinolinol, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In the event of a spill, it should be carefully cleaned up using appropriate methods and the incident should be documented. A safety data sheet (SDS) should always be consulted for detailed safety information.