How is 7-Methoxy-4-quinolinol (CAS: 82121-05-9) typically synthesized?

7-Methoxy-4-quinolinol is commonly synthesized via the methylation of 4-quinolinol using methanol and a strong base like sodium hydride. The reaction proceeds in an aprotic solvent at low temperature, yielding a high purity product with good selectivity. The process typically involves careful handling of reactive intermediates and proper cooling to prevent side reactions.