7-Methoxy-4-quinolinol(CAS: 82121-05-9)

7-Methoxy-4-quinolinol is a crystalline solid with a molecular weight of approximately 213.2 g/mol. It is poorly soluble in water but soluble in solvents like ethanol and dimethylformamide. The compound shows moderate reactivity and is stable under normal conditions. It is typically prepared in the solid state and can be used in various chemical reactions.

7-Methoxy-4-quinolinol is commonly synthesized via the methylation of 4-quinolinol using methanol and a strong base like sodium hydride. The reaction proceeds in an aprotic solvent at low temperature, yielding a high purity product with good selectivity. The process typically involves careful handling of reactive intermediates and proper cooling to prevent side reactions.

7-Methoxy-4-quinolinol is primarily used in the pharmaceutical industry for the synthesis of various bioactive compounds and in the production of certain dyes and pigments. It is also employed in the development of new materials for electronic and optoelectronic applications.

When handling 7-Methoxy-4-quinolinol, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In the event of a spill, it should be carefully cleaned up using appropriate methods and the incident should be documented. A safety data sheet (SDS) should always be consulted for detailed safety information.