(2-Fluoro-5-nitrophenyl)boronic acid

Basic Information

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CAS Number

819849-20-2

Molecular Formula

C6H5BFNO4

Molecular Weight

184.92 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

258-260°C

Boiling Point

366.8°C at 760 mmHg

Water Solubility

Slightly soluble in water.

SMILES

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B(C1=C(C=CC(=C1)[N+](=O)[O-])F)(O)O

InChI

InChI=1S/C6H5BFNO4/c8-6-2-1-4(9(12)13)3-5(6)7(10)11/h1-3,10-11H

InChIKey

SYAFEPQKPQIRAL-UHFFFAOYSA-N

LogP

-0.06310

Complexity

198

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-fluoro-5-nitro phenyl boronic acid
CS-W002992
J-509467
AKOS006346481
(2-fluoro-5-nitrophenyl)boronic acid
2-fluoro-5-nitrophenylboronicacid
AB13165
819849-20-2
CHEMBL5174005
AM20050335
2-Fluoro-5-nitrophenylboronic acid
SY032720
Boronic acid, (2-fluoro-5-nitrophenyl)-
BCP09214
EN300-7363514
SCHEMBL1199420
AS-17775
MFCD03092929
Z1201621988
2-fluoro-5-nitrobenzeneboronic acid
DTXSID30376866
FT-0658421
SYAFEPQKPQIRAL-UHFFFAOYSA-N
2-Fluoro-5-nitrobenzeneboronic acid
(2-Fluoro-5-nitrophenyl)boronic acid
KSC649E7N
PC3014
SBB065080
FCH920930
VB10789

MDL Number

MFCD03092929

Customs Code

2931900090

FAQ

What are the physical and chemical properties of (2-Fluoro-5-nitrophenyl)boronic acid (CAS: 819849-20-2)?

(2-Fluoro-5-nitrophenyl)boronic acid is a white or off-white crystalline solid with a molecular weight of approximately 288.06 g/mol. It is slightly soluble in water and ethanol. This compound is reactive towards nucleophiles and can undergo boronate ester formation. It is stable under normal conditions but should be handled with care to prevent decomposition.

How is (2-Fluoro-5-nitrophenyl)boronic acid (CAS: 819849-20-2) typically synthesized?

(2-Fluoro-5-nitrophenyl)boronic acid is typically synthesized through the reaction of 2-fluoro-5-nitrophenol with boron tribromide in anhydrous dichloromethane. This method provides a high yield and good selectivity. Other synthetic routes include the use of other boron sources like boronate esters or boronates under various conditions.

What industries use (2-Fluoro-5-nitrophenyl)boronic acid (CAS: 819849-20-2)?

(2-Fluoro-5-nitrophenyl)boronic acid is used in the pharmaceutical industry for the synthesis of drug precursors. It also finds applications in the polymer industry, particularly in the production of functional polymers. Additionally, it is used in the electronics industry for the development of sensors and semiconductors.

What precautions should be taken when handling (2-Fluoro-5-nitrophenyl)boronic acid (CAS: 819849-20-2)?

When handling (2-Fluoro-5-nitrophenyl)boronic acid, it is important to use appropriate personal protective equipment (PPE) such as gloves and safety goggles. This compound should be handled in a fume hood to minimize exposure. In case of a spill, it should be cleaned up using appropriate protective measures. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and follow all laboratory safety guidelines.