(2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol | CAS No. 81024-43-3

(2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol

Basic Information

CAS Number

81024-43-3

Molecular Formula

C15H25NO3

Molecular Weight

267.37 g/mol

AD

Basic Physical Properties

Melting Point

39-42°C

COCCc1ccc(OC[C@H](O)CNC(C)C)cc1

InChI

InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3/t14-/m1/s1

InChIKey

IUBSYMUCCVWXPE-CQSZACIVSA-N

LogP

1.6132

Topological Polar Surface Area

50.72 Ų

Hydrogen Bond Donor/Acceptor

2 / 4

Synonyms & References

English

  • 2-Propanol,1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R)-
  • (R)-(+)-METOPROLOL
  • (R)-Metoprolol
  • (+)-Metoprolol
  • (2R)-metoprolol
  • (R)-1-isopropylamino-3-[4-(2-metoxyethyl)phenoxy]propan-2-ol
  • BIDD:GT0581
  • d-Metoprolol
  • (R)-1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol

MDL Number

MFCD00869311

FAQ

What are the physical and chemical properties of (2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol (CAS: 81024-43-3)?

The compound (2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol has a crystalline form and a molecular weight of approximately 344.45 g/mol. It is slightly soluble in water and highly soluble in organic solvents. The compound is reactive towards nucleophiles and can undergo substitution reactions. It is stable under normal conditions but should be stored in a cool, dry place away from direct sunlight.

How is (2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol (CAS: 81024-43-3) typically synthesized?

The compound is typically synthesized via a multi-step process involving the formation of a phenol derivative, followed by alkylation and amino substitution reactions. The synthesis involves the use of suitable catalysts to ensure high selectivity and yield. The exact method can vary, but the reaction conditions, such as temperature and solvent, are crucial for optimal results.

What industries use (2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol (CAS: 81024-43-3)?

This compound is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for the modification of polymers and in the development of sensors and semiconductors for their unique chemical properties.

What precautions should be taken when handling (2R)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol (CAS: 81024-43-3)?

Handling this compound requires appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be conducted in a well-ventilated area or a fume hood to prevent inhaling fumes. Spills should be handled by the appropriate safety protocols, and the Material Safety Data Sheet (MSDS) should be consulted for detailed instructions. Ensure proper storage in a cool, dry place away from direct sunlight and flammable materials.

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