4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate

Basic Information

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CAS Number

80149-80-0

Molecular Formula

C12H17NO5Si

Molecular Weight

283.35 g/mol

Basic Physical Properties

Melting Point

37.0 to 41.0 deg-C

Boiling Point

371.7°C at 760 mmHg

Density

1.147

Water Solubility

Slightly soluble in water.

Flash Point

178.6 ºC

Refractive Index

1.503

SMILES

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C[Si](C)(C)CCOC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]

InChI

InChI=1S/C12H17NO5Si/c1-19(2,3)9-8-17-12(14)18-11-6-4-10(5-7-11)13(15)16/h4-7H,8-9H2,1-3H3

InChIKey

ZAQWGGKIMQIVGM-UHFFFAOYSA-N

LogP

3.97160

Complexity

315

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Moisture & Light Sensitive

Synonyms & References

English

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate
ZAQWGGKIMQIVGM-UHFFFAOYSA-N
4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate, >=95.0% (NMR)
80149-80-0
4-Nitrophenyl(2-(trimethylsilyl)ethyl)carbonate
C76565
A916078
Carbonic acid 4-nitro-phenyl ester-2-trimethylsilanyl-ethyl ester
4-nitrophenyl 2-trimethylsilylethyl carbonate
DTXSID10230093
C12H17NO5Si
2-trimethylsilanylethyl 4-nitrophenyl carbonate
SCHEMBL1161760
Carbonic acid, 4-nitrophenyl 2-(trimethylsilyl)ethyl ester
2-(trimethylsilyl)ethyl p-nitrophenyl carbonate
CS-0017956
EINECS 279-406-7
TEOC-ONp
carbonic acid 4-nitro-phenyl ester 2-trimethylsilanyl-ethyl ester
Tec-Onp
4-[2-(Trimethylsilyl)ethoxycarbonyloxy]nitrobenzene
T2872
AMY39305
FT-0702621
2-(Trimethylsilyl)ethyl 4-nitrophenyl carbonate
AS-11369
4-Nitrophenyl (2-(trimethylsilyl)ethyl) carbonate
J-515880
NS00060186
(4-nitrophenyl) 2-trimethylsilylethyl carbonate
AKOS016003283

MDL Number

MFCD00042930

Customs Code

2931900090

FAQ

What are the physical and chemical properties of 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0)?

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is a white crystalline solid with a molecular weight of approximately 355.25 g/mol. It has limited water solubility and is soluble in organic solvents like dichloromethane and acetone. This compound is known for its reactive nature, undergoing nucleophilic substitution reactions readily. It is used in organic synthesis as a protecting group for carboxylic acids.

How is 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) typically synthesized?

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is typically synthesized by the reaction of 4-nitrophenol with 2-(trimethylsilyl)ethyl chloroformate in the presence of a base such as triethylamine. The reaction is carried out under mild conditions, and the product can be purified by recrystallization or column chromatography.

What industries use 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0)?

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is primarily used in the pharmaceutical and chemical industries for the synthesis of various organic compounds. It is also utilized in polymer synthesis, particularly in the preparation of functionalized polymers, and in the production of sensors and semiconductors.

What precautions should be taken when handling 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0)?

When handling 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0), it is important to work in a well-ventilated area or fume hood to avoid inhalation of the compound. Wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and laboratory coat. Keep away from heat sources and oxidizing agents. In case of a spill, follow safety data sheet (SDS) guidelines for disposal and clean up. Always consult the latest SDS for specific handling instructions.