Compound Q&A

How is 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) typically synthesized?

Answer

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate
4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is typically synthesized by the reaction of 4-nitrophenol with 2-(trimethylsilyl)ethyl chloroformate in the presence of a base such as triethylamine. The reaction is carried out under mild conditions, and the product can be purified by recrystallization or column chromatography.

About

CAS No 80149-80-0
English Name 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate
Molecular Formula C12H17NO5Si
Molecular Weight 283.35 g/mol
SMILES C[Si](C)(C)CCOC(=O)OC1=CC=C(C=C1)[N+](=O)[O-]
InChIKey ZAQWGGKIMQIVGM-UHFFFAOYSA-N
Last Updated: 2025-09-29 09:43

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