4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate(CAS: 80149-80-0)

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is a white crystalline solid with a molecular weight of approximately 355.25 g/mol. It has limited water solubility and is soluble in organic solvents like dichloromethane and acetone. This compound is known for its reactive nature, undergoing nucleophilic substitution reactions readily. It is used in organic synthesis as a protecting group for carboxylic acids.

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is typically synthesized by the reaction of 4-nitrophenol with 2-(trimethylsilyl)ethyl chloroformate in the presence of a base such as triethylamine. The reaction is carried out under mild conditions, and the product can be purified by recrystallization or column chromatography.

4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0) is primarily used in the pharmaceutical and chemical industries for the synthesis of various organic compounds. It is also utilized in polymer synthesis, particularly in the preparation of functionalized polymers, and in the production of sensors and semiconductors.

When handling 4-Nitrophenyl 2-(trimethylsilyl)ethyl carbonate (CAS: 80149-80-0), it is important to work in a well-ventilated area or fume hood to avoid inhalation of the compound. Wear appropriate personal protective equipment (PPE), including safety goggles, gloves, and laboratory coat. Keep away from heat sources and oxidizing agents. In case of a spill, follow safety data sheet (SDS) guidelines for disposal and clean up. Always consult the latest SDS for specific handling instructions.