Sulfachloropyridazine

Basic Information

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CAS Number

80-32-0

Molecular Formula

C10H9ClN4O2S

Molecular Weight

284.73 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

186-187 ºC

Boiling Point

559.7°C at 760 mmHg

Density

1.588

Flash Point

292.3 °C

Solubility

0.5 M NaOH: soluble50mg/mL

Refractive Index

1.6300 (estimate)

SMILES

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C1=CC(=CC=C1N)S(=O)(=O)NC2=NN=C(C=C2)Cl

InChI

InChI=1S/C10H9ClN4O2S/c11-9-5-6-10(14-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)

InChIKey

XOXHILFPRYWFOD-UHFFFAOYSA-N

LogP

1.513

Topological Polar Surface Area

97.97 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

365

Safety Information

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GHS Hazard Pictograms

H317

Hazard Statement

H317 May cause an allergic skin reaction
Sensitization, Skin

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Vetisulid (Veterinary)
4-Amino-N-(6-chloropyridazin-3-yl)-benzenesulfonamide
N1-(6-Chloro-3-pyridazinyl)sulfanilamide
C76571
EINECS 201-269-9
[(4-aminophenyl)sulfonyl](6-chloropyridazin-3-yl)amine
4-Amino-N-(6-chloro-3-pyridazinyl)benzenesulfonamide
Spectrum3_001221
Sulphachlorpyridazine
4-amino-N-(6-chloropyridazin-3-yl)benzene-1-sulfonamide
SPECTRUM1501142
KBioSS_000587
BRD-K32021043-001-05-1
Sulfachlorpyridazinum
P78D9P90C0
4-AMINO-N-(6-CHLORO-3-PYRIDAZINYL)-1-BENZENESULFONAMIDE
Cosulid
KBio2_003155
NCGC00094909-01
AB00052217_11
SPBio_002850
SULFACHLORPYRIDAZINE [MI]
Spectrum4_000444
Solfaclorpiridazina [DCIT]
Sulfacloropiridazina [INN-Spanish]
Sulfacloropiridazina
Sulfachloropyridizine
NSC757858
HMS1921J11
HY-B1781
SPBio_002003

MDL Number

MFCD00057371

Customs Code

2935009090

FAQ

What are the physical and chemical properties of Sulfachloropyridazine (CAS: 80-32-0)?

Sulfachloropyridazine (CAS: 80-32-0) is a white to pale yellow crystalline solid with a molecular weight of approximately 266.77 g/mol. It is slightly soluble in water but more soluble in organic solvents. Chemically, it is relatively stable under normal conditions but can react with strong reducing agents. Its solubility and reactivity make it suitable for various applications in pharmaceuticals and agriculture.

How is Sulfachloropyridazine (CAS: 80-32-0) typically synthesized?

Sulfachloropyridazine (CAS: 80-32-0) is typically synthesized via a multi-step process starting with 2-chloropyridine and chloroacetyl chloride. Common synthesis methods involve the condensation of 2-chloropyridine with chloroacetyl chloride in the presence of a base, followed by further reactions to introduce the sulfonamide group. This process yields a high purity product with good selectivity and yield.

What industries use Sulfachloropyridazine (CAS: 80-32-0)?

Sulfachloropyridazine (CAS: 80-32-0) is primarily used in the pharmaceutical industry for the production of antibacterial drugs. It is also utilized in the agriculture sector as an intermediate for herbicides and pesticides. Its applications extend to industries involving polymer chemistry and as a component in various sensor technologies.

What precautions should be taken when handling Sulfachloropyridazine (CAS: 80-32-0)?

When handling Sulfachloropyridazine (CAS: 80-32-0), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation. Spills should be managed using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific guidelines on disposal and emergency procedures.