N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine | CAS No. 78888-06-9

N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine

Basic Information

CAS Number

78888-06-9

Molecular Formula

C26H24N2

Molecular Weight

364.49 g/mol

AD

Basic Physical Properties

CC1=CC(=CC=C1)NC2=CC=C(C=C2)C3=CC=C(C=C3)NC4=CC=CC(=C4)C

InChI

InChI=1S/C26H24N2/c1-19-5-3-7-25(17-19)27-23-13-9-21(10-14-23)22-11-15-24(16-12-22)28-26-8-4-6-20(2)18-26/h3-18,27-28H,1-2H3

InChIKey

ONKCIMOQGCARHN-UHFFFAOYSA-N

LogP

7.457640000000006

Topological Polar Surface Area

24.06 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

405

Synonyms & References

English

  • N,N-Di(3-Methylphenyl)Benzidine
  • FT-0657998
  • AKOS015903571
  • N4,N4'-Di-m-tolyl-[1,1'-biphenyl]-4,4'-diamine
  • A839526
  • n,n'-bis(3-methylphenyl)-(1,1'biphenyl)-4,4'-diamine
  • N,N'-bis(3-methylphenyl)benzidine
  • ONKCIMOQGCARHN-UHFFFAOYSA-N
  • N~4~,N~4'~-Bis(3-methylphenyl)[1,1'-biphenyl]-4,4'-diamine
  • 3-methyl-N-[4-[4-(3-methylanilino)phenyl]phenyl]aniline
  • SCHEMBL513478
  • SB82704
  • DTXSID10550622
  • 78888-06-9
  • N,N'-Bis(3-methylphenyl)-(1,1'-biphenyl)-4,4'-diamine
  • N,N'-di-(3-methylphenyl)-biphenyl-4,4'-diamine

MDL Number

MFCD10566504

Customs Code

2921590090

FAQ

What are the physical and chemical properties of N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine (CAS: 78888-06-9)?

N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine is a white to off-white crystalline solid with a molecular weight of approximately 296.3 g/mol. It has a high melting point of around 155-157°C and is slightly soluble in common organic solvents like ethanol and acetone. This compound is known to be chemically stable but can react under certain conditions to form polymers. It is generally non-toxic but may cause skin irritation if handled without proper protective equipment.

How is N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine (CAS: 78888-06-9) typically synthesized?

N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine is synthesized through the coupling of 4,4'-diaminobiphenyl with 3-methylphenyl isocyanate. This process typically uses a suitable catalyst such as triethylamine to promote the reaction. The yield is generally around 75-85%, and the reaction is carried out under anhydrous conditions to prevent side reactions. The product is typically purified by recrystallization from ethanol.

What industries use N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine (CAS: 78888-06-9)?

N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine is primarily used in the pharmaceutical and polymer industries. It is a key intermediate in the synthesis of various drugs and is also used in the preparation of advanced polymers for electronic and optical applications. This compound can also be used in the development of sensors and semiconductors due to its unique electronic and structural properties.

What precautions should be taken when handling N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine (CAS: 78888-06-9)?

When handling N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. In the event of a spill, the area should be ventilated and the spill cleaned up using appropriate absorbent materials. This compound is not considered highly hazardous, but it should be managed according to Material Safety Data Sheet (MSDS) guidelines. Always ensure proper ventilation and use a fume hood when handling this material.

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