Compound Q&A

How is N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine (CAS: 78888-06-9) typically synthesized?

Answer

N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine
N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine is synthesized through the coupling of 4,4'-diaminobiphenyl with 3-methylphenyl isocyanate. This process typically uses a suitable catalyst such as triethylamine to promote the reaction. The yield is generally around 75-85%, and the reaction is carried out under anhydrous conditions to prevent side reactions. The product is typically purified by recrystallization from ethanol.

About

CAS No 78888-06-9
English Name N,N'-Bis(3-methylphenyl)-4,4'-biphenyldiamine
Molecular Formula C26H24N2
Molecular Weight 364.49 g/mol
SMILES CC1=CC(=CC=C1)NC2=CC=C(C=C2)C3=CC=C(C=C3)NC4=CC=CC(=C4)C
InChIKey ONKCIMOQGCARHN-UHFFFAOYSA-N
Last Updated: 2026-03-11 12:33

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