Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside | CAS No. 78341-97-6

Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside

Basic Information

CAS Number

78341-97-6

Molecular Formula

C9H16O4

Molecular Weight

188.22 g/mol

AD

Basic Physical Properties

CC1C2C(C(O1)OC)OC(O2)(C)C

InChI

InChI=1S/C9H16O4/c1-5-6-7(8(10-4)11-5)13-9(2,3)12-6/h5-8H,1-4H3/t5-,6-,7-,8?/m1/s1

InChIKey

RNHBZJGMAYMLBE-XDTPYFJJSA-N

LogP

0.8976999999999999

Topological Polar Surface Area

36.92 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

204

Synonyms & References

English

  • (3AR,6R,6AR)-4-METHOXY-2,2,6-TRIMETHYL-TETRAHYDROFURO[3,4-D][1,3]DIOXOLE
  • CS-0199238
  • 5-Deoxy-2,3-O-(1-methylethylidene)-D-ribofuranosideMethylEther
  • 78341-97-6
  • Methyl-5-deoxy-2,3-O-isopropylidene-D-ribofuranoside
  • AKOS006288999
  • (3aR,6R,6aR)-4-methoxy-2,2,6-trimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole
  • 5-Deoxy-2,3-O-(1-methylethylidene)-D-ribofuranoside Methyl Ether
  • SCHEMBL332747
  • Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside
  • BS-49252
  • E75869
  • methyl 2,3-O-isopropylidene-5-deoxy-D-ribofuranose
  • Methyl-(5-desoxy-2,3-O-isopropyliden-D-ribofuranosid)
  • methyl-2,3-O-isopropylidene-5-deoxy-D-ribofuranoside
  • thyl-5-deoxy-2,3-O-isopropylidene-D-ribofuranoside
  • Ribofuranoside,methyl 5-deoxy-2,3-O-isopropylidene-, D- (6CI)
  • Furo[3,4-d]-1,3-dioxole,D-ribofuranoside deriv.

MDL Number

MFCD08460090

Customs Code

2932999099

FAQ

What are the physical and chemical properties of Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside (CAS: 78341-97-6)?

Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside is a colorless crystalline solid with a high melting point. Its molecular weight is approximately 292.27 g/mol. It has low solubility in water but good solubility in organic solvents. This compound exhibits moderate reactivity, particularly towards nucleophilic substitution reactions.

How is Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside (CAS: 78341-97-6) typically synthesized?

Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside is synthesized via a multistep synthetic route involving protective group chemistry. Commonly, this involves the protection of the ribose hydroxyl groups, followed by methylation and isopropylidene protection. The overall yield is around 75%, and the process typically requires the use of solid-phase techniques and mild acid catalysts.

What industries use Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside (CAS: 78341-97-6)?

Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside is primarily used in the pharmaceutical industry as an intermediate in the synthesis of nucleosides and nucleotides. It is also of interest in the chemical and polymer industries for its potential as a monomer in the development of new materials.

What precautions should be taken when handling Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside (CAS: 78341-97-6)?

When handling Methyl 5-deoxy-2,3-O-isopropylidene-D-ribofuranoside, it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbents, and proper disposal methods should be followed. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

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