Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate | CAS No. 775304-60-4
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
Basic Information
CAS Number
775304-60-4
Molecular Formula
C16H11FN2O3
Molecular Weight
298.27 g/mol
AD
Chemical Classification
Basic Physical Properties
Boiling Point
457.2±55.0°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, methyl ester
- methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- MLS002391460
- Methyl 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoate
- SMR001355430
- 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid methyl ester
- BDBM94057
- cid_11208732
- HMS3338H07
- HMS2201E09
- SY233501
- AK601638
- Benzoic acid,3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-,Methyl ester
- Benzoic a
- 775304-60-4
- Z1278904749
- NCGC00183594-01
- ALBB-036380
- F14761
- MFCD09971792
- SCHEMBL59495
- AKOS030524178
- CHEMBL1394246
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- CS-0059779
- DS-19714
- Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
MDL Number
MFCD09971792
FAQ
What are the physical and chemical properties of Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4)?
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is a crystalline compound with a molecular weight of approximately 303.27 g/mol. It is slightly soluble in water but highly soluble in organic solvents such as ethanol and acetonitrile. The compound exhibits good stability in air and is known for its reactivity in various organic reactions, particularly in condensation and substitution reactions.
How is Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4) typically synthesized?
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is commonly synthesized via a multistep process involving the condensation of 2-fluorophenyl isocyanate with 1,3-dibromo-5-(methylcarbamoyl)benzene, followed by the formation of the oxadiazole ring. The synthesis typically involves the use of palladium catalysts and requires careful temperature control to achieve high yield and selectivity.
What industries use Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4)?
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It also finds applications in the polymer industry for the development of advanced materials and in the sensor industry for the fabrication of chemical sensors due to its unique spectroscopic properties.
What precautions should be taken when handling Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4)?
When handling Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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