Compound Q&A
How is Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4) typically synthesized?
Answer
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is commonly synthesized via a multistep process involving the condensation of 2-fluorophenyl isocyanate with 1,3-dibromo-5-(methylcarbamoyl)benzene, followed by the formation of the oxadiazole ring. The synthesis typically involves the use of palladium catalysts and requires careful temperature control to achieve high yield and selectivity.
About
CAS No
775304-60-4
English Name
Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
Molecular Formula
C16H11FN2O3
Molecular Weight
298.27 g/mol
SMILES
COC(=O)C1=CC=CC(=C1)C2=NOC(=N2)C3=CC=CC=C3F
InChIKey
LFJJTHGQRVVGGN-UHFFFAOYSA-N
Last Updated: 2025-11-07 15:33
