Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate(CAS: 775304-60-4)

Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is a crystalline compound with a molecular weight of approximately 303.27 g/mol. It is slightly soluble in water but highly soluble in organic solvents such as ethanol and acetonitrile. The compound exhibits good stability in air and is known for its reactivity in various organic reactions, particularly in condensation and substitution reactions.

Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is commonly synthesized via a multistep process involving the condensation of 2-fluorophenyl isocyanate with 1,3-dibromo-5-(methylcarbamoyl)benzene, followed by the formation of the oxadiazole ring. The synthesis typically involves the use of palladium catalysts and requires careful temperature control to achieve high yield and selectivity.

Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate is primarily used in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs). It also finds applications in the polymer industry for the development of advanced materials and in the sensor industry for the fabrication of chemical sensors due to its unique spectroscopic properties.

When handling Methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate (CAS: 775304-60-4), it is essential to wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.