1-Fluoro-4-iodo-2-methoxybenzene

Basic Information

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CAS Number

773855-64-4

Molecular Formula

C7H6FIO

Molecular Weight

252.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

249.5°C at 760 mmHg

Density

1.803

Flash Point

104.7°C

Refractive Index

1.569

SMILES

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COC1=C(C=CC(=C1)I)F

InChI

InChI=1S/C7H6FIO/c1-10-7-4-5(9)2-3-6(7)8/h2-4H,1H3

InChIKey

FCDKZLAZICFOHU-UHFFFAOYSA-N

LogP

2.4389000000000003

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

110

Synonyms & References

English

SCHEMBL1477349
EN300-5122422
SY317141
FS-5244
Benzene, 1-fluoro-4-iodo-2-methoxy-
CS-0103252
MFCD09800754
SB38702
FCDKZLAZICFOHU-UHFFFAOYSA-N
YFB85564
DTXSID30650219
1-Fluoro-4-iodo-2-methoxybenzene
2-Fluoro-5-iodoanisole
AKOS016002458
A865271
FT-0702136
773855-64-4
2-fluoro-5-iodoanisole
AK-77853
ANW-57062
CTK8B7335
SureCN1477349
1-fluoro-4-iodo-2-methoxy-benzene
2100AC
TL80090135
ST24021321

MDL Number

MFCD09800754

FAQ

What are the physical and chemical properties of 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4)?

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) is a crystalline solid with a molecular weight of approximately 299.01 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity in electrophilic aromatic substitution reactions. It is a moderately reactive compound and should be handled with care due to its halogenated nature.

How is 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) typically synthesized?

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) can be synthesized via the protection of a methoxy group on a bromobenzene derivative followed by iodination. Commonly, this involves starting from 2-methoxybenzyl bromide, which is then iodinated using sodium iodide and a base like potassium carbonate in a suitable solvent such as acetonitrile. The resulting mixture is typically heated to promote the reaction.

What industries use 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4)?

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry as a monomer for the synthesis of certain polymers with specific properties. Additionally, this compound has applications in the semiconductor and sensor industries due to its unique chemical structure.

What precautions should be taken when handling 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4)?

When handling 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4), it is crucial to wear protective equipment such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood due to its potential to release harmful vapors. In case of a spill, it should be immediately contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information and procedures.