How is 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) typically synthesized?

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) can be synthesized via the protection of a methoxy group on a bromobenzene derivative followed by iodination. Commonly, this involves starting from 2-methoxybenzyl bromide, which is then iodinated using sodium iodide and a base like potassium carbonate in a suitable solvent such as acetonitrile. The resulting mixture is typically heated to promote the reaction.