1-Fluoro-4-iodo-2-methoxybenzene(CAS: 773855-64-4)

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) is a crystalline solid with a molecular weight of approximately 299.01 g/mol. It has a low solubility in water but is more soluble in organic solvents such as ethanol and acetone. The compound is known for its reactivity in electrophilic aromatic substitution reactions. It is a moderately reactive compound and should be handled with care due to its halogenated nature.

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) can be synthesized via the protection of a methoxy group on a bromobenzene derivative followed by iodination. Commonly, this involves starting from 2-methoxybenzyl bromide, which is then iodinated using sodium iodide and a base like potassium carbonate in a suitable solvent such as acetonitrile. The resulting mixture is typically heated to promote the reaction.

1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4) is primarily used in the pharmaceutical industry for the synthesis of various medicinal compounds. It is also utilized in the polymer industry as a monomer for the synthesis of certain polymers with specific properties. Additionally, this compound has applications in the semiconductor and sensor industries due to its unique chemical structure.

When handling 1-Fluoro-4-iodo-2-methoxybenzene (CAS: 773855-64-4), it is crucial to wear protective equipment such as gloves, goggles, and a lab coat. This compound should be handled in a fume hood due to its potential to release harmful vapors. In case of a spill, it should be immediately contained and cleaned up using appropriate absorbent materials. Always consult the Safety Data Sheet (SDS) for detailed safety information and procedures.