(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine | CAS No. 773127-33-6

(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine

Basic Information

CAS Number

773127-33-6

Molecular Formula

C9H10F3NO

Molecular Weight

205.18 g/mol

AD

Basic Physical Properties

COC1=CC=C(C=C1)C(C(F)(F)F)N

InChI

InChI=1S/C9H10F3NO/c1-14-7-4-2-6(3-5-7)8(13)9(10,11)12/h2-5,8H,13H2,1H3/t8-/m0/s1

InChIKey

WXWSEEIYIQOYNZ-QMMMGPOBSA-N

LogP

2.2573

Topological Polar Surface Area

35.25 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

175

Synonyms & References

English

  • (1S)-2,2,2-TRIFLUORO-1-(4-METHOXYPHENYL)ETHANAMINE
  • A865293
  • (S)-2,2,2-TRIFLUORO-1-(4-METHOXYPHENYL)ETHANAMINE
  • [(S)-alpha-(Trifluoromethyl)-4-methoxybenzyl]amine
  • MFCD07374546
  • WXWSEEIYIQOYNZ-QMMMGPOBSA-N
  • (1S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine
  • 773127-33-6
  • (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine
  • (1S)-2,2,2-TRIFLUORO-1-(4-METHOXYPHENYL)ETHYLAMINE
  • AKOS015924832
  • SCHEMBL13906582
  • AKOS015916960
  • (S)-2,2,2-Trifluoro-1-(4-methoxyphenyl)ethanamine

MDL Number

MFCD07374546

FAQ

What are the physical and chemical properties of (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine (CAS: 773127-33-6)?

(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine is a white crystalline solid with a molecular weight of approximately 256.08 g/mol. It has a low water solubility and is highly soluble in organic solvents like dichloromethane and chloroform. This compound is relatively unreactive but can undergo nucleophilic substitution reactions. It exhibits good stability under normal conditions but should be stored in a tightly sealed container away from moisture and heat.

How is (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine (CAS: 773127-33-6) typically synthesized?

(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine is typically synthesized by the reduction of trifluoroacetaldehyde with 4-methoxyphenylamine. Commonly, this reaction is catalyzed by palladium-based catalysts and proceeds with good selectivity and high yield. The exact conditions, such as temperature and solvent, can vary depending on the specific synthetic method used.

What industries use (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine (CAS: 773127-33-6)?

(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine is primarily used in the pharmaceutical industry for the synthesis of various drugs. It also finds applications in the polymer industry for the development of novel polymers and in the semiconductor industry for use as a dopant material. Additionally, it may be used in the production of sensors and analytical chemistry reagents.

What precautions should be taken when handling (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine (CAS: 773127-33-6)?

When handling (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coats. The compound should be handled in a well-ventilated area or a fume hood to minimize exposure. In the event of a spill, it should be carefully cleaned up using appropriate absorbents and the area should be thoroughly washed with water. Always refer to the Safety Data Sheet (SDS) for detailed information on safety measures and emergency procedures.

Related Compounds

You might also like

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...
Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide
Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...
Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...
Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...