Compound Q&A

How is (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine (CAS: 773127-33-6) typically synthesized?

Answer

(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine
(S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine is typically synthesized by the reduction of trifluoroacetaldehyde with 4-methoxyphenylamine. Commonly, this reaction is catalyzed by palladium-based catalysts and proceeds with good selectivity and high yield. The exact conditions, such as temperature and solvent, can vary depending on the specific synthetic method used.

About

English Name (S)-2,2,2-trifluoro-1-(4-methoxyphenyl)ethan-1-amine
Molecular Formula C9H10F3NO
Molecular Weight 205.18 g/mol
SMILES COC1=CC=C(C=C1)C(C(F)(F)F)N
InChIKey WXWSEEIYIQOYNZ-QMMMGPOBSA-N
Last Updated: 2026-03-19 14:17

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