N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (1:1) | CAS No. 7729-94-4

N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (1:1)

Basic Information

CAS Number

7729-94-4

Molecular Formula

C12H19ClN2O

Molecular Weight

242.75 g/mol

AD

Basic Physical Properties

CCNCC(=O)NC1=C(C=CC=C1C)C.Cl

InChI

InChI=1S/C12H18N2O.ClH/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3;/h5-7,13H,4,8H2,1-3H3,(H,14,15);1H

InChIKey

KPXFVVHMUVBVGI-UHFFFAOYSA-N

LogP

2.273240000000001

Topological Polar Surface Area

41.13 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

196

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • N-(2,6-dimethylphenyl)-N(2)-ethylglycinamide hydrochloride
  • CS-0151973
  • Q27124341
  • monoethylglycinexylidide hydrochloride
  • HY-W099331
  • N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamidehydrochloride
  • N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide;hydrochloride
  • Norlidocaine Hydrochloride (Monoethylglycinexylidide Hydrochloride)
  • MEGX hydrochloride
  • MEGX HCl
  • MFCD21334173
  • Nor Lidocaine Hydrochloride
  • 7729-94-4
  • MEGX (hydrochloride)
  • CHEBI:55524
  • N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide hydrochloride
  • N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide Hydrochloride (Monoethylglycinexylidide Hydrochloride)
  • N1171
  • Monoethylglycinexylidide (hydrochloride)
  • Norlidocaine Hydrochloride
  • NOR LIDOCAINE HCL
  • AS-83298
  • N-(2,6-Dimethylphenyl)-N<sup>2</sup>-ethylglycinamide hydrochloride (1:1)
  • NOR LIDOCAINE ,WHITE SOLID
  • Nor Lidocaine Hydroc
  • N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide Hydrochloride
  • Monoethylglycinexylidide Hydrochloride
  • LIDOCAINE IMPURITY D?EP?
  • Monoethylglycinexylidine HCl (Impurity D)
  • N-(2,6-dimethylphenyl)-2-(ethylamino)acetamide
  • hydrochloride (1:1)

MDL Number

MFCD21334173

FAQ

What are the physical and chemical properties of N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4)?

N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4) is a white crystalline solid. Its molecular weight is approximately 291.3 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is relatively stable and has good chemical and thermal stability. It is also non-flammable and non-explosive.

How is N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4) typically synthesized?

N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4) is typically synthesized via the condensation of 2,6-dimethylbenzylamine with ethyl glycinate in the presence of an acid catalyst, such as hydrochloric acid. The reaction is carried out under standard stirring conditions, and the product is isolated by crystallization from the reaction mixture. The yield is typically around 85-90%.

What industries use N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4)?

N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4) is used in various industries. It is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It is also used in the polymer industry as a modifier and in the production of sensors and semiconductors for electronic applications.

What precautions should be taken when handling N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4)?

When handling N-(2,6-Dimethylphenyl)-N~2~-ethylglycinamide hydrochloride (CAS: 7729-94-4), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled with caution and cleaned up immediately using appropriate disposal methods. Safety data sheets (SDS) should be consulted for detailed handling and emergency procedures.

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