1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (1:1)

Basic Information

View in Editor

CAS Number

77174-66-4

Molecular Formula

C18H16Cl2N2O

Molecular Weight

347.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

142-150°C

SMILES

View in Editor

C=C(C1=CC=CC=C1OCC2=CC(=CC=C2)Cl)N3C=CN=C3.Cl

InChI

InChI=1S/C18H15ClN2O.ClH/c1-14(21-10-9-20-13-21)17-7-2-3-8-18(17)22-12-15-5-4-6-16(19)11-15;/h2-11,13H,1,12H2;1H

InChIKey

LWJUIYYIILPRRI-UHFFFAOYSA-N

LogP

5.056300000000004

Topological Polar Surface Area

27.05 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

376

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Toxicity

LD50 in rats (mg/kg): 7000 s.c.; 2500 orally (Ogata, 1983)

Synonyms & References

English

1H-Imidazole, 1-(1-(2-((3-chlorobenzyl)oxy)phenyl)vinyl)-, monohydrochloride
Pilzcin
1-(1-O-(m-(Chlorobenzyloxy)phenyl)vinyl)-1H-imidazole hydrochloride
Croconazol clorhidrato
Cloconazole HCl
D02169
I0WFH323HZ
1-(1-(2-((3-Chlorophenyl)methoxy)phenyl)ethenyl)-1H-imidazole hydrochloride
1-(1-(2-(3-chlorobenzyloxy)phenyl)vinyl)-1H-imidazole hydrochloride
CROCONAZOLEHYDROCHLORIDE
Croconazol clorhidrato [Spanish]
1-(1-(2-((3-Chlorobenzyl)oxy)phenyl)vinyl)-1H-imidazole hydrochloride
Q27280216
Croconazole hydrochloride (JP17)
1-(1-(2-((3-Clorobenzil)oxi)fenil)vinil)-1H-imidazol monoclorhidrato
croconazole hydrochloride
SCHEMBL36790
Croconazole monohydrochloride
Croconazole Hydrochloride [JAN]
1-(1-(2-((3-Clorobenzil)oxi)fenil)vinil)-1H-imidazol monoclorhidrato [Spanish]
710674S
1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]imidazole hydrochloride
Cloconazole hydrochloride
710674-S
AKOS037643334
1-(1-(2-((3-Clorofenil)metoxi)fenil)etenil)-1H-imidazol monoclorhidrato
CROCONAZOLE HYDROCHLORIDE [WHO-DD]
77174-66-4
1-(1-(O-((M-CHLOROBENZYL)OXY)PHENYL)VINYL)IMIDAZOLE HYDROCHLORIDE
1H-Imidazole, 1-(1-(2-((3-chlorophenyl)methoxy)phenyl)ethenyl)-, monohydrochloride
AMY32538

MDL Number

MFCD00941395

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride crystallizes as a white powder with a molecular weight of approximately 456.8 g/mol. It is slightly soluble in water and ethanol, and has poor solubility in most organic solvents. This compound exhibits moderate reactivity towards nucleophiles and can undergo substitution reactions. It is stable under usual storage conditions but should be protected from moisture and strong acids.

How is 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4) typically synthesized?

1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride is typically synthesized via a multi-step reaction sequence involving protection, functionalization, and coupling of the intermediates. The synthesis involves the use of standard organic reaction conditions such as reflux, stirring, and the application of appropriate catalysts and solvents. The yield ranges from 50% to 70%, depending on the purity of the intermediates and the efficiency of the purification steps.

What industries use 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride is primarily used in pharmaceutical research and development, particularly for the synthesis of intermediates in drug discovery. It can also be used in the chemical industry for the development of new materials and sensors. In semiconductor manufacturing, it may serve as a precursor in the fabrication of electronic materials due to its unique chemical properties.

What precautions should be taken when handling 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

Precautions for handling 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride include the use of personal protective equipment such as gloves, goggles, and lab coats. It should be handled in a well-ventilated area or a fume hood to minimize exposure to vapors. Spills should be cleaned up with appropriate absorbent materials, and the area should be thoroughly cleaned afterwards. The material safety data sheet (MSDS) should be consulted for detailed safety information and emergency procedures.

Related Compounds

N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide

CAS Number: 1013920-15-4

Molecular Formula: C23H26FN5O3

7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure

Compound Q&A

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...

21889-89-46-Methyl-7-oxabicycl...

Compound Q&A

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...

906353-00-24-[(6-Methyl-2-pyraz...

Compound Q&A

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...

49745-42-82-(2-Pyridinyl)-1,3-...

Compound Q&A

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...

24783-42-42-(6-Chloro-2-pyridi...

Compound Q&A

What is 2-Oxopropanamide (CAS: 631-66-3)?

2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...

631-66-32-Oxopropanamide

Compound Q&A

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...

1289040-88-52-Methyl-2-propanyl ...

Compound Q&A

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...

2241019-57-6NAMPT inhibitor-link...

Compound Q&A

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...

1310404-58-0(2-(2,2,2-Trifluoroa...

Compound Q&A

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...

794568-90-41-(2-Chlorophenyl)-6...

Compound Q&A

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...

1314981-48-0Vinyl(chloromethyl)d...

1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (1:1) | CAS No. 77174-66-4

Basic Information

CAS Number

Molecular Formula

Molecular Weight

Chemical Classification

Basic Physical Properties

Melting Point

Chemical Properties

SMILES

InChI

InChIKey

LogP

Topological Polar Surface Area

Hydrogen Bond Donor/Acceptor

Complexity

Safety Information

Hazard Statement

Toxicity

Synonyms & References

English

MDL Number

Customs Code

FAQ

What are the physical and chemical properties of 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

How is 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4) typically synthesized?

What industries use 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

What precautions should be taken when handling 1-(1-{2-[(3-Chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole hydrochloride (CAS: 77174-66-4)?

Related Compounds

You might also like

What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?

What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?

What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?

What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?

What is 2-Oxopropanamide (CAS: 631-66-3)?

What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?

What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?

What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?

What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?

What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?

Supplier Information

Shanghai Hansi Chemical Co., Ltd.

Shanghai Jixiang Biotechnology Co., Ltd.

Shanghai Aladdin Bio-Technologies Co., Ltd.

Shanghai Kailing Industrial Development Co., Ltd.

Jiangsu Province Yangzhou Tend Chemical Factory

JACS- ZhengZhouJieKeSiHuaGongChanPin Co Ltd

Yantai Bosen Pharmaceutical Technology Co., Ltd.

Honest Joy Holdings Limited

ShenZhenAiTaHuaXue Co Ltd

Product Inquiry