4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone | CAS No. 765948-78-5
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone
Basic Information
CAS Number
765948-78-5
Molecular Formula
C14H18BNO3
Molecular Weight
259.11 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- AKOS015901463
- AM20120456
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one
- CXNFLUANJNYFBF-UHFFFAOYSA-N
- P11181
- PB20614
- 4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-2,3-DIHYDRO-ISOINDOL-1-ONE
- DTXSID70619880
- 1-Oxoisoindoline-4-boronic Acid Pinacol Ester
- Z2049763545
- A838759
- J-513438
- MFCD11617913
- 1H-Isoindol-1-one, 2,3-dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- BCP26419
- 4-(4,4,5,5-Tetramethyl-1,3,2- dioxaborolan-2-yl)isoindolin-1-one
- 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-isoindol-1-one
- SCHEMBL1335533
- EN300-816108
- (1-OXOISOINDOLIN-4-YL)BORONIC ACID PINACOL ESTER
- AS-50818
- 4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLIN-1-ONE
- CS-0051135
- SY068368
- 2,3-Dihydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-isoindol-1-one
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydroisoindol-1-one
- 1-Oxo-2,3-dihydro-isoindole-4-boronic acid pinacol ester
- 765948-78-5
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone
- A9706
- 2,3-DIHYDRO-1H-ISOINDOL-1-ONE-4-BORONIC ACID PINACOL ESTER
MDL Number
MFCD11617913
Customs Code
2931900090
FAQ
What are the physical and chemical properties of 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone (CAS: 765948-78-5)?
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone is a crystalline compound with a molecular weight of approximately 324.37 g/mol. It has a low solubility in water but is more soluble in organic solvents like DMF and DMSO. Chemically, it is stable under normal conditions but reacts with strong acids and bases. It can be used in synthesis as a boron-containing reagent.
How is 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone (CAS: 765948-78-5) typically synthesized?
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone is synthesized via a multi-step process involving the protection of 1-isoindolinone, followed by the introduction of a boron-containing group. Commonly, this involves using Boc-protected 1-isoindolinone and a boronic acid in the presence of a catalytic amount of palladium, a base, and a suitable solvent.
What industries use 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone (CAS: 765948-78-5)?
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone is utilized in pharmaceuticals for its role as a building block in medicinal chemistry. It also finds application in the synthesis of polymers and sensors, particularly in the development of boron-containing materials for electronic and optical applications.
What precautions should be taken when handling 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone (CAS: 765948-78-5)?
Handling 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone requires the use of personal protective equipment (PPE) including gloves, goggles, and lab coat. Work in a well-ventilated area or fume hood to minimize exposure. Spills should be cleaned up using appropriate decontamination procedures, and the Material Safety Data Sheet (MSDS) should be consulted for detailed safety information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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