Compound Q&A
How is 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone (CAS: 765948-78-5) typically synthesized?
Answer
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone is synthesized via a multi-step process involving the protection of 1-isoindolinone, followed by the introduction of a boron-containing group. Commonly, this involves using Boc-protected 1-isoindolinone and a boronic acid in the presence of a catalytic amount of palladium, a base, and a suitable solvent.
About
CAS No
765948-78-5
English Name
4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-isoindolinone
Molecular Formula
C14H18BNO3
Molecular Weight
259.11 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=C3CNC(=O)C3=CC=C2
InChIKey
CXNFLUANJNYFBF-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24
