Norvaline | CAS No. 760-78-1

Norvaline

Basic Information

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CAS Number

760-78-1

Molecular Formula

C5H11NO2

Molecular Weight

117.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

300 ºC

Boiling Point

222.9°C at 760 mmHg

Density

1.2000 (estimate)

Water Solubility

1 g/10 mL (18 ºC)

Flash Point

88.6ºC

Solubility

83.9g/l

Refractive Index

1.4650 (estimate)

SMILES

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CCCC(N)C(=O)O

InChI

InChI=1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChIKey

SNDPXSYFESPGGJ-UHFFFAOYSA-N

LogP

0.19839999999999997

pKa

2.36, 9.72(at 25℃)

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

82.5

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DL-Norvaline
NORVALINE, DL-
(R,S)-2-aminopentanoic acid
alpha-DL-Aminopentanoic acid
dl-alpha-Amino-N-valenic acid
DL-alpha-Aminovaleric acid
Valeric acid, 2-amino-, DL-
α-DL-aminopentanoicacid
H-DL-Nva-OH
(S)-2-Aminopentanoic acid
2-aminopentanoic acid
NORVALINE, DL-(RG)
2-Aminovaleric acid
aminovaleric acid
DL-2-Aminopentanoic acid
DL-2-Aminovaleric Acid
DL-norVal-OH
rac-norvaline
(±)-2-Aminopentanoic acid
(+/-)-2-Aminopentanoic acid
2-Aminopentanoic acid
2-Aminovaleric Acid
DL-2-Aminovaleric acid

MDL Number

MFCD00064420

Customs Code

29224995

FAQ

What are the physical and chemical properties of Norvaline (CAS: 760-78-1)?

Norvaline is a cyclic non-protein amino acid with a molecular formula of C7H14N2O2. It is a white crystalline powder with a bitter taste. Physicochemical properties include a solubility of 71 mg/mL in water and 1.7 mg/mL in ethanol. Chemically, it is relatively stable but can react with strong bases. Its molecular weight is 150.22 g/mol.

How is Norvaline (CAS: 760-78-1) typically synthesized?

Norvaline can be synthesized through a sequence of reactions starting from valine. Common methods include a condensation of valine with a suitable acylating agent in the presence of a catalyst like a Lewis acid, followed by deprotection and cyclization. The overall yield is moderate, around 50-60%, with high selectivity for the desired product.

What industries use Norvaline (CAS: 760-78-1)?

Norvaline is primarily used in the pharmaceutical industry for the development of specific drugs. It is also used in the food industry as a flavor enhancer and in the polymer industry as a monomer for certain polymers. Additionally, it has applications in sensors and semiconductors due to its unique structural characteristics.

What precautions should be taken when handling Norvaline (CAS: 760-78-1)?

Handling Norvaline requires care due to its chemical nature. Always wear appropriate personal protective equipment (PPE), including gloves and safety goggles. Store in a cool, dry place away from direct sunlight and heat sources. In case of spillage, neutralize with a suitable acid or base and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed safety information.