Compound Q&A

How is Norvaline (CAS: 760-78-1) typically synthesized?

Answer

Norvaline
Norvaline can be synthesized through a sequence of reactions starting from valine. Common methods include a condensation of valine with a suitable acylating agent in the presence of a catalyst like a Lewis acid, followed by deprotection and cyclization. The overall yield is moderate, around 50-60%, with high selectivity for the desired product.

About

CAS No 760-78-1
English Name Norvaline
Molecular Formula C5H11NO2
Molecular Weight 117.14799999999998 g/mol
SMILES CCCC(N)C(=O)O
InChIKey SNDPXSYFESPGGJ-UHFFFAOYSA-N
Last Updated: 2025-09-07 10:18

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