2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Basic Information

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CAS Number

7576-65-0

Molecular Formula

C18H11NO3

Molecular Weight

289.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

>360°C

Boiling Point

502ºC

Density

1.435

Refractive Index

1.4800 (estimate)

SMILES

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Oc1cc2ccccc2nc1C1C(=O)c2c(C1=O)cccc2

InChI

InChI=1S/C18H11NO3/c20-14-9-10-5-1-4-8-13(10)19-16(14)15-17(21)11-6-2-3-7-12(11)18(15)22/h1-9,15,20H

InChIKey

FDTLQXNAPKJJAM-UHFFFAOYSA-N

LogP

3.103200000000001

Topological Polar Surface Area

67.26 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

453

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-(3-hydroxy-2-quinolyl)-1H-indene-1,3(2H)-dione
3-Hydroxy-2-(1,3-indandione-2-yl)quinoline
SOLVENTYELLOW 114
2-(3-Hydroxy-[2]chinolyl)-indan-1,3-dion
2-(3-hydroxy-[2]quinolyl)-indan-1,3-dione
2-(3-hydroxy-quinolin-2-yl)-indan-1,3-dione
3'-hydroxyquinophthalone
C.I.Solvent Yellow 114
kayaset yellow a-g
macrolex yellow g
nsc 64849
Oil Yellow 114
plast yellow 8040
PS Yellow GG
resiren yellow tgl
samaron yellow 3gl
SOLVENT YELLOW
2-(3-Hydroxy-2-quinolyl)-1,3-indandione
2-(3-Hydroxyquinolin-2-yl)-1H-indene-1,3(2H)-dione
3-Hydroxyquinophthalone
C.I. 47020
Disperse Yellow 54
Disperse Yellow E 2G
Di

MDL Number

MFCD00266981

FAQ

What are the physical and chemical properties of 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 7576-65-0)?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione is a crystalline compound with a molecular weight of approximately 311.27 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and ethanol. This compound exhibits good stability under normal conditions but can degrade under strong acidic or basic conditions. It is also known to react readily with nucleophiles and electrophiles, making it useful in various chemical transformations.

How is 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 7576-65-0) typically synthesized?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione is typically synthesized via a multi-step process that involves the reaction of 2-(3-hydroxy-2-quinolinyl)indene with a suitable reagent under mild conditions. Common methods include the use of acid or base catalysis, which can lead to high yields and good selectivity. The exact synthetic route can vary depending on the availability of starting materials and desired product purity.

What industries use 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 7576-65-0)?

2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione is primarily used in the pharmaceutical and materials science industries. It serves as a key intermediate in the synthesis of various pharmaceuticals and is also explored for its potential applications in the development of advanced polymers, sensors, and semiconductors. Its unique chemical properties make it valuable for these applications.

What precautions should be taken when handling 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione (CAS: 7576-65-0)?

When handling 2-(3-Hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to avoid inhalation of any vapors. Spills should be cleaned up using appropriate chemicals and tools, and the area should be properly decontaminated. Users should always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.