4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide

Basic Information

View in Editor

CAS Number

757251-39-1

Molecular Formula

C13H12FN3O2

Molecular Weight

261.26 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

141.0 to 145.0 deg-C

Density

1.305

SMILES

View in Editor

CNC(=O)c1nccc(c1)Oc1ccc(c(c1)F)N

InChI

InChI=1S/C13H12FN3O2/c1-16-13(18)12-7-9(4-5-17-12)19-8-2-3-11(15)10(14)6-8/h2-7H,15H2,1H3,(H,16,18)

InChIKey

ZQHJPIPGBODVTG-UHFFFAOYSA-N

LogP

1.9547999999999999

Topological Polar Surface Area

77.24 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

316

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide
2-Pyridinecarboxamide,4-(4-amino-3-fluorophenoxy)-N-methyl-
4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxylic acid methylamide
4-(4-Amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYL-2-PYRIDINECARBOXAMIDE
4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide EINECS
4-(4-AMINO-3-FLUOROPHENOXY)-N-METHYLPICOLIMIDE
Regorafenib Intermediate
AK119007
ZQHJPIPGBODVTG-UHFFFAOYSA-N
2-Pyridinecarboxamide, 4-(4-amino-3-fluorophenoxy)-N-methyl-
BCP04468
4-(4-amino-3-fluoro-phenoxy)-pyridine-2-carboxylic acid methylamide
4-(4-amino-3-fluorophenoxy)-N-methylpyridine-2-carboxamide
4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide

MDL Number

MFCD09033852

FAQ

What is 4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1)?

4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) is a chemical compound containing a picolinamide group linked to a 4-amino-3-fluorophenoxy moiety. It is characterized by its molecular structure, which includes an aromatic ring with fluorine and amino substituents, making it relevant in pharmaceutical and chemical research. The compound is known for its potential biological activity and is often studied for its applications in drug development.

What are the main uses of 4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1)?

4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) is primarily used in pharmaceutical research as a potential lead compound for drug development. It may serve as an intermediate in the synthesis of various bioactive molecules. Additionally, it finds applications in chemical synthesis and can be relevant in studies related to medicinal chemistry and organic reactions.

Is 4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) safe?

The safety of 4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) depends on its specific application and exposure conditions. It is generally considered safe when handled properly in controlled environments. However, standard safety precautions should be followed, including the use of protective equipment and ensuring proper ventilation. Safety data sheets (SDS) should be consulted for detailed handling guidelines.

How should 4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) be stored?

4-(4-Amino-3-fluorophenoxy)-n-methylpicolinamide (CAS: 757251-39-1) should be stored in a cool, dry, and well-ventilated place, away from light and moisture. It is typically kept in a sealed container to maintain its stability. Storage conditions should be maintained at a temperature below 25°C and humidity levels below 60% to prevent degradation and ensure long-term integrity.