CHAPS | CAS No. 75621-03-3

CHAPS

Basic Information

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CAS Number

75621-03-3

Molecular Formula

C32H58N2O7S

Molecular Weight

614.9 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Basic Physical Properties

Melting Point

156-158°C (dec.)

Density

1.01 g/mL at 20 °C

Water Solubility

Soluble in water (10 mg/ml). Soluble in DMF and hot methanol.

Solubility

H2O: 50 mg/mL at 20 °C, clear, colorless

Refractive Index

1.6900 (estimate)

SMILES

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CC(CCC(=O)NCCC[N+](C)(C)CCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C

InChI

InChI=1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1

InChIKey

UMCMPZBLKLEWAF-BCTGSCMUSA-N

LogP

4.35380

Complexity

1030

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Moisture Sensitive: Hydroscopic

Sensitiveness

Hygroscopic

Synonyms & References

English

3-((3-Cholamidopropyl)dimethylammonio)-1-propanesulfonate
3-[(3-cholamidopropyl)-dimethylammonio]-1-propane-sulfonate
CHEMBL450950
3-[dimethyl(3-{[(3beta,5alpha,7alpha,12alpha,14beta,17alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino}propyl)ammonio]propane-1-sulfonate
NS00125721
3-[(3-cholamidopropyl)dimethylammonium]-1-propansulfonate
CHEBI:1418
3-((3-cholamidopropyl)dimethylammonio)-1-propanesulphonate
3-((3-Cholamidopropyl)dimethylammonium)-1-propanesulfonate
1-Propanaminium, N,N-dimethyl-3-sulfo-N-(3-(((3alpha,5beta,7alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)propyl)-,hydroxide, inner salt
1-Propanaminium, N,N-dimethyl-N-(3-sulfopropyl)-3-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)-, hydroxide, inner salt
DS-14351
CS-0926
UNII-QBP25342AG
1-PROPANAMINIUM, N,N-DIMETHYL-N-(3-SULFOPROPYL)-3-(((3.ALPHA.,5.BETA.,7.ALPHA.,12.ALPHA.)-3,7,12-TRIHYDROXY-24-OXOCHOLAN-24-YL)AMINO)-, INNER SALT
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE
3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulphonate
DTXSID70997059
A865651
1-Propanaminium,N,N-dimethyl-N-(3-sulfopropyl)-3-[[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-, inner salt
AKOS027399767
3-[(3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate
J-018379
CHAPS
75621-03-3
QBP25342AG
3-(Dimethyl{3-[(3,7,12,24-tetrahydroxycholan-24-ylidene)amino]propyl}azaniumyl)propane-1-sulfonate
3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]ammonio]propane-1-sulfonate
SCHEMBL116864
3-(3-Cholamidopropyl)dimethylammonio-1-propanesulfonate
Cholic acid sulfobetaine1-propanaminium, N,N-dimethyl-3-sulfo-N-(3-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)propyl)-, hydroxide, inner salt

MDL Number

MFCD00012116

Customs Code

2934999090

FAQ

What is CHAPS (CAS: 75621-03-3)?

CHAPS, or 3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonic acid, is a zwitterionic surfactant commonly used in biochemical applications. It has the chemical formula C12H26N2O6S and is known for its ability to solubilize hydrophobic substances in aqueous solutions. CHAPS is non-ionic and has a neutral charge at physiological pH, making it suitable for preserving protein structures and facilitating purification processes.

What are the main uses of CHAPS (CAS: 75621-03-3)?

CHAPS is widely used in pharmaceuticals, biotechnology, and research for its role as a detergent and solubilizing agent. It helps in the extraction and purification of membrane proteins, stabilizes proteins during storage, and is used in the formulation of liquid detergents. Additionally, CHAPS finds applications in the food industry as an emulsifier and in industrial processes for cleaning and dispersing applications.

Is CHAPS (CAS: 75621-03-3) safe?

CHAPS is generally considered safe when used under proper conditions, but it should be handled with care. It has low toxicity and is not classified as a hazardous substance under most safety standards. However, prolonged skin contact or inhalation may cause irritation, so protective gloves and masks are recommended. Always follow standard laboratory safety protocols when working with CHAPS.

How should CHAPS (CAS: 75621-03-3) be stored?

CHAPS should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is typically kept in a sealed container at a temperature range of 15–25°C. Maintaining proper humidity levels is essential to prevent degradation, and it should be stored in a non-corrosive, airtight container to ensure stability and prolong shelf life.